Gene Ontology

Gene Info

  • Species:Rat (Rattus norvegicus)
  • GeneID:24766
  • Symbol:Scn2a
  • Description:sodium voltage-gated channel alpha subunit 2

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
24766 GO:0001518 IDA part_of voltage-gated sodium channel complex 2442385,15664695 Component
24766 GO:0005886 IDA located_in plasma membrane 24297919,28029095 Component
24766 GO:0030424 IDA located_in axon 22473424 Component
24766 GO:0033268 IDA located_in node of Ranvier 16652168 Component
24766 GO:0034706 IDA part_of sodium channel complex 24297919 Component
24766 GO:0043194 IDA located_in axon initial segment 12036953 Component

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
24766 GO:0005248 IDA enables voltage-gated sodium channel activity 2442385,15664695,24297919,28029095 Function
24766 GO:0005515 IPI enables protein binding 10737807,21439835 Function
24766 GO:0031402 IDA enables sodium ion binding 15664695 Function
24766 GO:0043522 IPI enables leucine zipper domain binding 17360357 Function
24766 GO:0099508 IDA enables voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 25615535 Function
24766 GO:0099508 IMP enables voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 25615535 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
24766 GO:0006814 IDA involved_in sodium ion transport 2442385 Process
24766 GO:0019228 IDA involved_in neuronal action potential 15664695,15917456 Process
24766 GO:0021554 IEP involved_in optic nerve development 22473424 Process
24766 GO:0021987 IEP involved_in cerebral cortex development 22473424 Process
24766 GO:0022038 IEP involved_in corpus callosum development 22473424 Process
24766 GO:0035725 IDA involved_in sodium ion transmembrane transport 24297919,28029095 Process
24766 GO:0042552 IEP involved_in myelination 16652168 Process
24766 GO:0061564 IEP involved_in axon development 22473424 Process
24766 GO:0071456 IDA involved_in cellular response to hypoxia 28029095 Process