Gene Ontology

Gene Info

  • Species:Rat (Rattus norvegicus)
  • GeneID:25054
  • Symbol:Ntrk2
  • Description:neurotrophic receptor tyrosine kinase 2

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
25054 GO:0004714 IMP enables transmembrane receptor protein tyrosine kinase activity 17447135 Function
25054 GO:0005030 IDA enables neurotrophin receptor activity 16477614 Function
25054 GO:0005030 IMP enables neurotrophin receptor activity 16983663 Function
25054 GO:0005515 IPI enables protein binding 9582017,17341134,18957540,19126684,21364532,21775604..... Function
25054 GO:0030971 IPI enables receptor tyrosine kinase binding 16801538 Function
25054 GO:0042803 IDA enables protein homodimerization activity 8627351 Function
25054 GO:0043121 IDA enables neurotrophin binding 1645620 Function
25054 GO:0048403 IDA enables brain-derived neurotrophic factor binding 1645620,16477614 Function
25054 GO:0048403 IMP enables brain-derived neurotrophic factor binding 16983663 Function
25054 GO:0060175 IDA enables brain-derived neurotrophic factor receptor activity 1645620,8627351 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
25054 GO:0005886 IDA located_in plasma membrane 1645620 Component
25054 GO:0009986 IDA located_in cell surface 17079678 Component
25054 GO:0030424 IDA located_in axon 17079678,21775604 Component
25054 GO:0030425 IDA located_in dendrite 17079678,21775604 Component
25054 GO:0030426 IDA located_in growth cone 17079678 Component
25054 GO:0043025 IDA located_in neuronal cell body 17079678 Component
25054 GO:0043197 IDA located_in dendritic spine 18582438,25632160 Component
25054 GO:0043204 IDA located_in perikaryon 16626872 Component
25054 GO:0043679 IDA located_in axon terminus 18582438 Component
25054 GO:0045211 IDA is_active_in postsynaptic membrane 10679783 Component
25054 GO:0048471 IDA located_in perinuclear region of cytoplasm 21775604 Component
25054 GO:0048786 IDA located_in presynaptic active zone 16477614 Component
25054 GO:0060076 IDA located_in excitatory synapse 17079678 Component
25054 GO:0098794 IDA is_active_in postsynapse 25632160 Component
25054 GO:0098794 IMP is_active_in postsynapse 25632160 Component
25054 GO:0098978 IDA is_active_in glutamatergic synapse 10679783,25632160 Component
25054 GO:0098978 IMP is_active_in glutamatergic synapse 25632160 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
25054 GO:0007616 IDA involved_in long-term memory 21136519 Process
25054 GO:0008284 IDA involved_in positive regulation of cell population proliferation 9582017 Process
25054 GO:0009416 IEP involved_in response to light stimulus 17640634 Process
25054 GO:0010996 IEP involved_in response to auditory stimulus 21034795 Process
25054 GO:0014068 IMP involved_in positive regulation of phosphatidylinositol 3-kinase signaling 10985347 Process
25054 GO:0031547 IDA involved_in brain-derived neurotrophic factor receptor signaling pathway 1645620,8627351 Process
25054 GO:0031547 IMP involved_in brain-derived neurotrophic factor receptor signaling pathway 15654844 Process
25054 GO:0043408 IDA involved_in regulation of MAPK cascade 9582017 Process
25054 GO:0043410 IMP involved_in positive regulation of MAPK cascade 10985347 Process
25054 GO:0043524 IMP involved_in negative regulation of neuron apoptotic process 10985347 Process
25054 GO:0046777 IDA involved_in protein autophosphorylation 9582017 Process
25054 GO:0046777 IMP involved_in protein autophosphorylation 17447135 Process
25054 GO:0046928 IDA involved_in regulation of neurotransmitter secretion 16477614 Process
25054 GO:0050772 IMP involved_in positive regulation of axonogenesis 10985347 Process
25054 GO:0050773 IMP involved_in regulation of dendrite development 15654844 Process
25054 GO:0051968 IMP involved_in positive regulation of synaptic transmission, glutamatergic 16983663 Process
25054 GO:0071356 IEP involved_in cellular response to tumor necrosis factor 21958434 Process
25054 GO:1990090 IEP involved_in cellular response to nerve growth factor stimulus 21958434 Process
25054 GO:1990416 IEP involved_in cellular response to brain-derived neurotrophic factor stimulus 21958434 Process
25054 GO:2000324 IGI acts_upstream_of_or_within positive regulation of glucocorticoid receptor signaling pathway 23878391 Process