Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:2521
  • Symbol:FUS
  • Description:FUS RNA binding protein

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2521 GO:0003682 IDA enables chromatin binding 25453086,27731383 Function
2521 GO:0003713 IDA enables transcription coactivator activity 21909421 Function
2521 GO:0003723 EXP enables RNA binding 29677513 Function
2521 GO:0003723 HDA enables RNA binding 22658674,22681889 Function
2521 GO:0003723 IDA enables RNA binding 27378374 Function
2521 GO:0005515 IPI enables protein binding 9774382,16169070,18509338,18954305,20085233,21988832,22240165,..... Function
2521 GO:0042802 IPI enables identical protein binding 18509338,23975937,29439243,29610493 Function
2521 GO:0140693 IDA enables molecular condensate scaffold activity 26317470,26455390,29677513 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2521 GO:0005634 IDA located_in nucleus 16365397,21909421,27731383 Component
2521 GO:0005654 IDA located_in nucleoplasm Component
2521 GO:0043232 IDA is_active_in intracellular non-membrane-bounded organelle 21541367,22579281,26317470 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2521 GO:0006355 IDA involved_in regulation of DNA-templated transcription 26124092 Process
2521 GO:0006357 IDA involved_in regulation of transcription by RNA polymerase II 25453086 Process
2521 GO:0008380 IDA involved_in RNA splicing 26124092 Process
2521 GO:0043484 IDA involved_in regulation of RNA splicing 25453086,27731383 Process
2521 GO:0048255 IDA acts_upstream_of_or_within mRNA stabilization 27378374 Process
2521 GO:0051260 IDA involved_in protein homooligomerization 25453086 Process
2521 GO:1905168 IDA involved_in positive regulation of double-strand break repair via homologous recombination 10567410 Process
2521 GO:1990000 EXP involved_in amyloid fibril formation 28942918 Process
2521 GO:1990000 IDA involved_in amyloid fibril formation 22579281 Process