Gene Ontology

Gene Info

  • Species:Rat (Rattus norvegicus)
  • GeneID:25262
  • Symbol:Itpr1
  • Description:inositol 1,4,5-trisphosphate receptor, type 1

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
25262 GO:0005220 IDA enables inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity 15533917,19036964 Function
25262 GO:0005515 IPI enables protein binding 12676536,12873381,15911880,16103111,19036964,21424589,22045699..... Function
25262 GO:0019903 IDA enables protein phosphatase binding 15212990 Function
25262 GO:0042802 IPI enables identical protein binding 21827954,23479737,26458101 Function
25262 GO:0044325 IPI enables transmembrane transporter binding 23982204 Function
25262 GO:0044877 IDA enables protein-containing complex binding 15212990 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
25262 GO:0005635 IDA located_in nuclear envelope 16014380 Component
25262 GO:0005789 IDA located_in endoplasmic reticulum membrane 15533917,15911880 Component
25262 GO:0016020 IDA is_active_in membrane 1311032 Component
25262 GO:0016529 IDA located_in sarcoplasmic reticulum 16014380 Component
25262 GO:0030425 IDA located_in dendrite 17471556 Component
25262 GO:0030868 IDA is_active_in smooth endoplasmic reticulum membrane 1311032 Component
25262 GO:0032991 IDA part_of protein-containing complex 12676536 Component
25262 GO:0043025 IDA located_in neuronal cell body 17471556 Component
25262 GO:0048471 IDA located_in perinuclear region of cytoplasm 12615969 Component
25262 GO:0097060 IDA located_in synaptic membrane 12676536 Component
25262 GO:0098793 IDA is_active_in presynapse 1311032 Component
25262 GO:0098794 IDA is_active_in postsynapse 1311032 Component
25262 GO:0098982 IDA is_active_in GABA-ergic synapse 1311032 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
25262 GO:0007204 IMP involved_in positive regulation of cytosolic calcium ion concentration 15911880,24814243 Process
25262 GO:0010976 IMP involved_in positive regulation of neuron projection development 21211516 Process
25262 GO:0016358 IEP involved_in dendrite development 19236309 Process
25262 GO:0043065 IMP involved_in positive regulation of apoptotic process 28072885 Process
25262 GO:0043066 IMP involved_in negative regulation of apoptotic process 20434434 Process
25262 GO:0051209 IMP involved_in release of sequestered calcium ion into cytosol 16223735 Process
25262 GO:0051928 IDA involved_in positive regulation of calcium ion transport 19036964 Process
25262 GO:0071320 IDA involved_in cellular response to cAMP 20189985 Process
25262 GO:0071456 IEP involved_in cellular response to hypoxia 17285299 Process
25262 GO:0097421 IMP involved_in liver regeneration 24814243 Process
25262 GO:2000347 IMP involved_in positive regulation of hepatocyte proliferation 24814243 Process