Gene Ontology

Gene Info

  • Species:Rat (Rattus norvegicus)
  • GeneID:25369
  • Symbol:Adora2a
  • Description:adenosine A2a receptor

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
25369 GO:0001609 IDA enables G protein-coupled adenosine receptor activity 12590138 Function
25369 GO:0005515 IPI enables protein binding 16617164,17356572,23994616 Function
25369 GO:0031802 IPI enables type 5 metabotropic glutamate receptor binding 12189203 Function
25369 GO:0044877 IPI enables protein-containing complex binding 16481441 Function
25369 GO:0051393 IDA enables alpha-actinin binding 12837758 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
25369 GO:0001973 IDA involved_in G protein-coupled adenosine receptor signaling pathway 12590138 Process
25369 GO:0006355 IDA involved_in regulation of DNA-templated transcription 12189203 Process
25369 GO:0006469 IDA involved_in negative regulation of protein kinase activity 12590138 Process
25369 GO:0007189 IMP involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway 16478979 Process
25369 GO:0007205 IDA involved_in protein kinase C-activating G protein-coupled receptor signaling pathway 12590138 Process
25369 GO:0007271 IMP involved_in synaptic transmission, cholinergic 15297571 Process
25369 GO:0007626 IMP involved_in locomotory behavior 12827647 Process
25369 GO:0008285 IDA involved_in negative regulation of cell population proliferation 16617164 Process
25369 GO:0009410 IEP involved_in response to xenobiotic stimulus 17853654 Process
25369 GO:0014049 IDA involved_in positive regulation of glutamate secretion 16481441 Process
25369 GO:0014057 IMP involved_in positive regulation of acetylcholine secretion, neurotransmission 12679375 Process
25369 GO:0014061 IMP involved_in regulation of norepinephrine secretion 16539684 Process
25369 GO:0031000 IDA involved_in response to caffeine 16481441 Process
25369 GO:0035249 IDA involved_in synaptic transmission, glutamatergic 16644907 Process
25369 GO:0035810 IMP involved_in positive regulation of urine volume 10070140 Process
25369 GO:0042311 IMP involved_in vasodilation 10070140,16601261 Process
25369 GO:0042755 IMP involved_in eating behavior 12827647 Process
25369 GO:0043116 IMP involved_in negative regulation of vascular permeability 16815983 Process
25369 GO:0043154 IDA involved_in negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 15211592 Process
25369 GO:0043279 IMP involved_in response to alkaloid 16684876 Process
25369 GO:0043524 IDA involved_in negative regulation of neuron apoptotic process 15211592 Process
25369 GO:0045938 IDA involved_in positive regulation of circadian sleep/wake cycle, sleep 16109808 Process
25369 GO:0048143 IMP involved_in astrocyte activation 12838511 Process
25369 GO:0048812 IDA involved_in neuron projection morphogenesis 16617164 Process
25369 GO:0048812 IMP involved_in neuron projection morphogenesis 12727227 Process
25369 GO:0050714 IDA involved_in positive regulation of protein secretion 14742743 Process
25369 GO:0051881 IDA involved_in regulation of mitochondrial membrane potential 15211592 Process
25369 GO:0051899 IMP involved_in membrane depolarization 16644907 Process
25369 GO:0051924 IMP involved_in regulation of calcium ion transport 15297571 Process
25369 GO:0051968 IDA involved_in positive regulation of synaptic transmission, glutamatergic 16481441 Process
25369 GO:0060079 IDA involved_in excitatory postsynaptic potential 16644907 Process
25369 GO:0060134 IMP involved_in prepulse inhibition 12827647 Process
25369 GO:0099171 EXP involved_in presynaptic modulation of chemical synaptic transmission 15659214 Process
25369 GO:0099171 IDA involved_in presynaptic modulation of chemical synaptic transmission 15659214 Process
25369 GO:0099171 IEP involved_in presynaptic modulation of chemical synaptic transmission 15659214 Process
25369 GO:1900273 IMP involved_in positive regulation of long-term synaptic potentiation 14596853 Process

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
25369 GO:0005882 IDA colocalizes_with intermediate filament 16644907 Component
25369 GO:0005886 IDA located_in plasma membrane 23994616 Component
25369 GO:0030424 IDA located_in axon 16952160 Component
25369 GO:0030425 IDA located_in dendrite 16952160 Component
25369 GO:0030673 IDA located_in axolemma 16481441 Component
25369 GO:0032279 IDA located_in asymmetric synapse 16481441 Component
25369 GO:0042734 IDA is_active_in presynaptic membrane 16952160 Component
25369 GO:0042734 IDA located_in presynaptic membrane 16481441,16952160 Component
25369 GO:0043025 IDA located_in neuronal cell body 16644907 Component
25369 GO:0045211 IDA is_active_in postsynaptic membrane 16952160 Component
25369 GO:0045211 IDA located_in postsynaptic membrane 16481441,16952160 Component
25369 GO:0048786 IDA located_in presynaptic active zone 16481441 Component
25369 GO:0098978 EXP is_active_in glutamatergic synapse 15659214 Component
25369 GO:0098978 IDA is_active_in glutamatergic synapse 15659214 Component