Gene Ontology

Gene Info

• Species:Rat (Rattus norvegicus)
• GeneID:25402
• Symbol:Casp3
• Description:caspase 3

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
25402	GO:0001554	IEP	involved_in	luteolysis	25332219	Process
25402	GO:0001666	IEP	involved_in	response to hypoxia	18466900,24089674	Process
25402	GO:0006508	IDA	involved_in	proteolysis	17553422	Process
25402	GO:0007413	IMP	involved_in	axonal fasciculation	25898930	Process
25402	GO:0007611	IMP	involved_in	learning or memory	18239768	Process
25402	GO:0009410	IEP	involved_in	response to xenobiotic stimulus	18274634	Process
25402	GO:0009749	IDA	involved_in	response to glucose	19356108	Process
25402	GO:0010033	IEP	involved_in	response to organic substance	18490855	Process
25402	GO:0010038	IEP	involved_in	response to metal ion	18483861	Process
25402	GO:0010165	IEP	involved_in	response to X-ray	18239382	Process
25402	GO:0014070	IEP	involved_in	response to organic cyclic compound	18255115	Process
25402	GO:0021766	IEP	involved_in	hippocampus development	18459132	Process
25402	GO:0030163	IDA	involved_in	protein catabolic process	15004018,18316105	Process
25402	GO:0030182	IEP	involved_in	neuron differentiation	15248196	Process
25402	GO:0031647	IDA	involved_in	regulation of protein stability	17553422	Process
25402	GO:0032025	IEP	involved_in	response to cobalt ion	18598848	Process
25402	GO:0032355	IEP	involved_in	response to estradiol	18598848	Process
25402	GO:0032496	IEP	involved_in	response to lipopolysaccharide	18289516	Process
25402	GO:0034349	IEP	involved_in	glial cell apoptotic process	18931364	Process
25402	GO:0035094	IEP	involved_in	response to nicotine	18477628	Process
25402	GO:0035556	IMP	involved_in	intracellular signal transduction	12492473	Process
25402	GO:0042542	IDA	involved_in	response to hydrogen peroxide	18479463	Process
25402	GO:0043065	IMP	involved_in	positive regulation of apoptotic process	17869439	Process
25402	GO:0043200	IEP	involved_in	response to amino acid	18423997	Process
25402	GO:0043525	IMP	involved_in	positive regulation of neuron apoptotic process	18404518	Process
25402	GO:0051146	IEP	involved_in	striated muscle cell differentiation	28899909	Process
25402	GO:0051384	IEP	involved_in	response to glucocorticoid	18288275	Process
25402	GO:0071407	IEP	involved_in	cellular response to organic cyclic compound	16987298	Process
25402	GO:0071887	IEP	involved_in	leukocyte apoptotic process	26861981	Process
25402	GO:1902004	IDA	involved_in	positive regulation of amyloid-beta formation	17553422	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
25402	GO:0002020	IPI	enables	protease binding	17518537	Function
25402	GO:0005123	IPI	enables	death receptor binding	17518537	Function
25402	GO:0005515	IPI	enables	protein binding	18485100	Function
25402	GO:0008234	IDA	enables	cysteine-type peptidase activity	16336964,17182030,17218406,18316105	Function
25402	GO:0016005	IMP	enables	phospholipase A2 activator activity	12492473	Function
25402	GO:0044877	IPI	enables	protein-containing complex binding	17518537	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
25402	GO:0031264	IDA	part_of	death-inducing signaling complex	17518537	Component
25402	GO:0043025	IDA	located_in	neuronal cell body	25898930	Component