Gene Ontology

Gene Info

  • Species:Rat (Rattus norvegicus)
  • GeneID:25553
  • Symbol:Slc6a4
  • Description:solute carrier family 6 member 4

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
25553 GO:0001666 IEP involved_in response to hypoxia 11259539 Process
25553 GO:0006837 IDA involved_in serotonin transport 11709063 Process
25553 GO:0006837 IMP involved_in serotonin transport 15994310 Process
25553 GO:0007584 IEP involved_in response to nutrient 21068163 Process
25553 GO:0007613 IMP involved_in memory 20730799 Process
25553 GO:0007623 IMP involved_in circadian rhythm 18482738 Process
25553 GO:0009410 IEP involved_in response to xenobiotic stimulus 20501324 Process
25553 GO:0010033 IEP involved_in response to organic substance 20002520 Process
25553 GO:0014064 IMP involved_in positive regulation of serotonin secretion 25261262 Process
25553 GO:0021941 IMP involved_in negative regulation of cerebellar granule cell precursor proliferation 18573488 Process
25553 GO:0032227 IMP involved_in negative regulation of synaptic transmission, dopaminergic 20730799 Process
25553 GO:0032355 IEP involved_in response to estradiol 19168037 Process
25553 GO:0042310 IMP involved_in vasoconstriction 14605793 Process
25553 GO:0042713 IMP involved_in sperm ejaculation 20704641 Process
25553 GO:0045665 IMP involved_in negative regulation of neuron differentiation 18573488 Process
25553 GO:0051610 IDA involved_in serotonin uptake 10716733,14642278,15627510 Process
25553 GO:0051610 IMP involved_in serotonin uptake Process
25553 GO:0051899 IDA involved_in membrane depolarization 14642278 Process
25553 GO:0071300 IEP involved_in cellular response to retinoic acid 17895527 Process
25553 GO:0071321 IDA involved_in cellular response to cGMP 17310063 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
25553 GO:0005261 IDA enables monoatomic cation channel activity 8968583,14642278 Function
25553 GO:0005335 IDA enables serotonin:sodium:chloride symporter activity 1944572,10407194,10716733,11709063,15627510 Function
25553 GO:0005335 IMP enables serotonin:sodium:chloride symporter activity 8601815,15994310 Function
25553 GO:0005515 IPI enables protein binding 16870614 Function
25553 GO:0017075 IPI enables syntaxin-1 binding 11709063,14642278 Function
25553 GO:0019811 IMP enables cocaine binding 15994310 Function
25553 GO:0042802 IMP enables identical protein binding Function
25553 GO:0042802 IPI enables identical protein binding 10716733 Function
25553 GO:0051015 IDA enables actin filament binding 15627510 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
25553 GO:0005886 IDA located_in plasma membrane 8601815,10716733,11709063,15627510 Component
25553 GO:0012505 IDA located_in endomembrane system 16870614 Component
25553 GO:0042734 IDA is_active_in presynaptic membrane 10460242 Component
25553 GO:0045211 IDA is_active_in postsynaptic membrane 10460242 Component
25553 GO:0099154 IDA is_active_in serotonergic synapse 10460242 Component