Gene Ontology

Gene Info

  • Species:Rat (Rattus norvegicus)
  • GeneID:25614
  • Symbol:Ptk2
  • Description:protein tyrosine kinase 2

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
25614 GO:0000165 IMP involved_in MAPK cascade 12764094 Process
25614 GO:0007229 IDA involved_in integrin-mediated signaling pathway 22973009 Process
25614 GO:0007254 IMP involved_in JNK cascade 12782622 Process
25614 GO:0009410 IEP involved_in response to xenobiotic stimulus 16249671 Process
25614 GO:0009612 IEP involved_in response to mechanical stimulus 18359002 Process
25614 GO:0009749 IEP involved_in response to glucose 14969714 Process
25614 GO:0010033 IEP involved_in response to organic substance 15194624 Process
25614 GO:0010243 IEP involved_in response to organonitrogen compound 15194624 Process
25614 GO:0014070 IEP involved_in response to organic cyclic compound 15063155 Process
25614 GO:0014911 IMP involved_in positive regulation of smooth muscle cell migration 12133282 Process
25614 GO:0030307 IMP involved_in positive regulation of cell growth 16923336 Process
25614 GO:0030335 IMP involved_in positive regulation of cell migration 12631140 Process
25614 GO:0030336 IMP involved_in negative regulation of cell migration 16899713 Process
25614 GO:0030644 IMP involved_in intracellular chloride ion homeostasis 16040720 Process
25614 GO:0032355 IEP involved_in response to estradiol 17412802 Process
25614 GO:0042311 IMP involved_in vasodilation 16195476 Process
25614 GO:0043066 IMP involved_in negative regulation of apoptotic process 16825486 Process
25614 GO:0045444 IEP involved_in fat cell differentiation 17442274 Process
25614 GO:0045785 IMP involved_in positive regulation of cell adhesion 12133282 Process
25614 GO:0046685 IEP involved_in response to arsenic-containing substance 15537746 Process
25614 GO:0048661 IMP involved_in positive regulation of smooth muscle cell proliferation 15208331 Process
25614 GO:0050766 IMP involved_in positive regulation of phagocytosis 12912913 Process
25614 GO:0050806 IMP involved_in positive regulation of synaptic transmission 12764094 Process
25614 GO:0060252 IMP involved_in positive regulation of glial cell proliferation 12838510 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
25614 GO:0005178 IPI enables integrin binding 16935300,18465789 Function
25614 GO:0005515 IPI enables protein binding 12473661,12629171,16690621,19470647,21383007,22106313..... Function
25614 GO:0019902 IDA enables phosphatase binding 22609523 Function
25614 GO:0042802 IPI enables identical protein binding 24480479 Function
25614 GO:0043548 IPI enables phosphatidylinositol 3-kinase binding 18854312 Function
25614 GO:0044877 IPI enables protein-containing complex binding 12912913,16935300 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
25614 GO:0005925 IDA located_in focal adhesion 17027000 Component
25614 GO:0014704 IDA located_in intercalated disc 18194601 Component
25614 GO:0016323 IDA located_in basolateral plasma membrane 17620366 Component
25614 GO:0016324 IDA located_in apical plasma membrane 12912913 Component
25614 GO:0016604 IDA located_in nuclear body 16373587 Component
25614 GO:0042383 IDA located_in sarcolemma 12124360 Component
25614 GO:0043197 IDA located_in dendritic spine 22973009 Component
25614 GO:0098794 IDA is_active_in postsynapse 22973009,27518800 Component
25614 GO:0098978 IDA is_active_in glutamatergic synapse 22973009,27518800 Component