Gene Ontology

Gene Info

• Species:Human (Homo sapiens)
• GeneID:260434
• Symbol:PYDC1
• Description:pyrin domain containing 1

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
260434	GO:0005515	IPI	enables	protein binding	12656673	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
260434	GO:0005634	IDA	located_in	nucleus	12656673	Component
260434	GO:0005829	IDA	located_in	cytosol	12656673	Component
260434	GO:0008385	IDA	part_of	IkappaB kinase complex	12656673	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
260434	GO:0006469	IDA	involved_in	negative regulation of protein kinase activity	12656673	Process
260434	GO:0010804	IMP	involved_in	negative regulation of tumor necrosis factor-mediated signaling pathway	24871464	Process
260434	GO:0032088	IDA	involved_in	negative regulation of NF-kappaB transcription factor activity	12656673	Process
260434	GO:0032088	IMP	NOT involved_in	negative regulation of NF-kappaB transcription factor activity	24871464	Process
260434	GO:0032691	IMP	NOT involved_in	negative regulation of interleukin-1 beta production	24871464	Process
260434	GO:0032731	IDA	involved_in	positive regulation of interleukin-1 beta production	12656673	Process
260434	GO:0033209	IDA	involved_in	tumor necrosis factor-mediated signaling pathway	12656673	Process
260434	GO:0045087	IDA	involved_in	innate immune response	12656673	Process
260434	GO:1900226	IMP	NOT involved_in	negative regulation of NLRP3 inflammasome complex assembly	24871464	Process