Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:2621
  • Symbol:GAS6
  • Description:growth arrest specific 6

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2621 GO:0001786 IDA enables phosphatidylserine binding 21501828 Function
2621 GO:0005102 IDA enables signaling receptor binding 16359517 Function
2621 GO:0005102 IPI enables signaling receptor binding 7854420 Function
2621 GO:0005515 IPI enables protein binding 18760998,20088931,20103767 Function
2621 GO:0030296 IDA enables protein tyrosine kinase activator activity 20103767 Function
2621 GO:0030674 IDA enables protein-macromolecule adaptor activity 21501828 Function
2621 GO:0030971 IPI enables receptor tyrosine kinase binding 7634325 Function
2621 GO:0043027 IDA enables cysteine-type endopeptidase inhibitor activity involved in apoptotic process 16723520 Function
2621 GO:0048018 IDA enables receptor ligand activity 15184064 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2621 GO:0001934 IDA involved_in positive regulation of protein phosphorylation 7854420,16723520,20103767 Process
2621 GO:0001961 IMP involved_in positive regulation of cytokine-mediated signaling pathway 18840707 Process
2621 GO:0006468 IDA involved_in protein phosphorylation 16359517 Process
2621 GO:0006909 IDA involved_in phagocytosis 21501828 Process
2621 GO:0007165 IDA involved_in signal transduction 7854420,18680538 Process
2621 GO:0010628 IDA involved_in positive regulation of gene expression 19657094 Process
2621 GO:0010804 IDA involved_in negative regulation of tumor necrosis factor-mediated signaling pathway 19657094 Process
2621 GO:0018105 IDA involved_in peptidyl-serine phosphorylation 18680538,20103767 Process
2621 GO:0019064 IDA involved_in fusion of virus membrane with host plasma membrane 21501828 Process
2621 GO:0019079 IDA involved_in viral genome replication 21501828 Process
2621 GO:0032689 IDA involved_in negative regulation of type II interferon production 18840707 Process
2621 GO:0032692 IDA involved_in negative regulation of interleukin-1 production 20103767 Process
2621 GO:0032715 IDA involved_in negative regulation of interleukin-6 production 19657094,20103767 Process
2621 GO:0032720 IDA involved_in negative regulation of tumor necrosis factor production 19657094,20103767 Process
2621 GO:0032825 IDA involved_in positive regulation of natural killer cell differentiation 18840707 Process
2621 GO:0033138 IDA involved_in positive regulation of peptidyl-serine phosphorylation 16723520 Process
2621 GO:0035457 IDA involved_in cellular response to interferon-alpha 19657094 Process
2621 GO:0035754 IDA involved_in B cell chemotaxis 19922767 Process
2621 GO:0043066 IDA involved_in negative regulation of apoptotic process 19922767 Process
2621 GO:0043154 IDA involved_in negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 16723520 Process
2621 GO:0043277 IDA involved_in apoptotic cell clearance 21501828 Process
2621 GO:0043433 IDA involved_in negative regulation of DNA-binding transcription factor activity 18680538 Process
2621 GO:0043491 IDA involved_in protein kinase B signaling 16723520,20103767 Process
2621 GO:0045860 IDA involved_in positive regulation of protein kinase activity 7854420 Process
2621 GO:0045892 IDA involved_in negative regulation of DNA-templated transcription 18680538 Process
2621 GO:0046718 IDA involved_in viral entry into host cell 21501828 Process
2621 GO:0046813 IDA involved_in receptor-mediated virion attachment to host cell 21501828 Process
2621 GO:0046827 IDA involved_in positive regulation of protein export from nucleus 18680538 Process
2621 GO:0048146 IDA acts_upstream_of_or_within positive regulation of fibroblast proliferation 15184064 Process
2621 GO:0048146 IDA involved_in positive regulation of fibroblast proliferation 7854420 Process
2621 GO:0050766 IDA involved_in positive regulation of phagocytosis 18395422 Process
2621 GO:0051897 IDA involved_in positive regulation of protein kinase B signaling 16359517,16723520,18680538 Process
2621 GO:0061098 IDA involved_in positive regulation of protein tyrosine kinase activity 20103767 Process
2621 GO:0070168 IDA involved_in negative regulation of biomineral tissue development 20048160 Process
2621 GO:0070374 IDA acts_upstream_of_or_within positive regulation of ERK1 and ERK2 cascade 15184064 Process
2621 GO:0070588 IDA involved_in calcium ion transmembrane transport 18395422 Process
2621 GO:0071307 IDA involved_in cellular response to vitamin K 16359517 Process
2621 GO:0071466 IDA involved_in cellular response to xenobiotic stimulus 16359517 Process
2621 GO:0072659 IDA involved_in protein localization to plasma membrane 16359517 Process
2621 GO:0097028 IEP involved_in dendritic cell differentiation 19657094 Process
2621 GO:0097241 IDA involved_in hematopoietic stem cell migration to bone marrow 19922767 Process
2621 GO:1900142 IDA involved_in negative regulation of oligodendrocyte apoptotic process 16723520 Process
2621 GO:2000270 IDA involved_in negative regulation of fibroblast apoptotic process 16359517 Process
2621 GO:2000352 IDA involved_in negative regulation of endothelial cell apoptotic process 16359517,18680538,18760998 Process
2621 GO:2000510 IDA involved_in positive regulation of dendritic cell chemotaxis 19657094 Process
2621 GO:2000669 IDA involved_in negative regulation of dendritic cell apoptotic process 19657094 Process

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2621 GO:0005615 IDA located_in extracellular space 8336730,18395422,19922767,20088931 Component
2621 GO:0005737 IDA located_in cytoplasm 18395422 Component
2621 GO:0070062 HDA located_in extracellular exosome 23533145 Component