Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:26401
  • Symbol:Map3k1
  • Description:mitogen-activated protein kinase kinase kinase 1

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
26401 GO:0000165 IDA acts_upstream_of_or_within MAPK cascade 14967141 Process
26401 GO:0002011 IMP acts_upstream_of_or_within morphogenesis of an epithelial sheet 25224220 Process
26401 GO:0003382 IMP acts_upstream_of_or_within epithelial cell morphogenesis 23201579 Process
26401 GO:0007179 IMP acts_upstream_of_or_within transforming growth factor beta receptor signaling pathway 12941696 Process
26401 GO:0007254 IDA acts_upstream_of_or_within JNK cascade 14967141 Process
26401 GO:0008637 IMP acts_upstream_of_or_within apoptotic mitochondrial changes 15882989 Process
26401 GO:0030334 IMP acts_upstream_of_or_within regulation of cell migration 12941696 Process
26401 GO:0030838 IMP acts_upstream_of_or_within positive regulation of actin filament polymerization 12941696,25224220 Process
26401 GO:0042060 IMP acts_upstream_of_or_within wound healing 12941696 Process
26401 GO:0043010 IMP acts_upstream_of_or_within camera-type eye development 12941696 Process
26401 GO:0043507 IDA involved_in positive regulation of JUN kinase activity 10523642 Process
26401 GO:0061029 IMP acts_upstream_of_or_within eyelid development in camera-type eye 23201579,25224220 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
26401 GO:0004706 IDA enables JUN kinase kinase kinase activity 14967141 Function
26401 GO:0004708 EXP enables MAP kinase kinase activity 9065412,9078260 Function
26401 GO:0005515 IPI enables protein binding 10523642,12826667,14500727,17681137,25260751 Function
26401 GO:0008092 IDA enables cytoskeletal protein binding 25224220 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
26401 GO:0031941 IDA part_of filamentous actin 25224220 Component