Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:26404
  • Symbol:Map3k12
  • Description:mitogen-activated protein kinase kinase kinase 12

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
26404 GO:0004674 IDA enables protein serine/threonine kinase activity 7983011,8663324 Function
26404 GO:0004674 IMP enables protein serine/threonine kinase activity 27511108 Function
26404 GO:0042803 IDA enables protein homodimerization activity 8663324 Function
26404 GO:0043539 IMP enables protein serine/threonine kinase activator activity 27511108 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
26404 GO:0005829 IDA located_in cytosol 8663324 Component
26404 GO:0005886 IDA located_in plasma membrane 8663324 Component
26404 GO:0030424 IDA located_in axon 18031680 Component
26404 GO:0030426 IDA located_in growth cone 18031680 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
26404 GO:0007254 IMP involved_in JNK cascade 27511108 Process
26404 GO:0018105 IDA involved_in peptidyl-serine phosphorylation 7983011 Process
26404 GO:0018105 IMP involved_in peptidyl-serine phosphorylation 27511108 Process
26404 GO:0018107 IDA involved_in peptidyl-threonine phosphorylation 7983011 Process
26404 GO:0043507 IMP involved_in positive regulation of JUN kinase activity 27511108 Process
26404 GO:0043687 IDA involved_in post-translational protein modification 8663324 Process
26404 GO:0045860 IMP involved_in positive regulation of protein kinase activity 27511108 Process
26404 GO:0046777 IDA involved_in protein autophosphorylation 7983011,8663324 Process
26404 GO:2000672 IMP acts_upstream_of_or_within negative regulation of motor neuron apoptotic process 25100604 Process