Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:26409
  • Symbol:Map3k7
  • Description:mitogen-activated protein kinase kinase kinase 7

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
26409 GO:0000165 IDA acts_upstream_of_or_within MAPK cascade 12556533 Process
26409 GO:0000165 IMP involved_in MAPK cascade 20551513 Process
26409 GO:0001525 IMP acts_upstream_of_or_within angiogenesis 16556914 Process
26409 GO:0001649 IMP involved_in osteoblast differentiation 20551513 Process
26409 GO:0001841 IMP acts_upstream_of_or_within neural tube formation 16260493 Process
26409 GO:0006468 IDA acts_upstream_of_or_within protein phosphorylation 12464436 Process
26409 GO:0006468 IDA involved_in protein phosphorylation 28842570 Process
26409 GO:0007179 IMP acts_upstream_of_or_within transforming growth factor beta receptor signaling pathway 16145668 Process
26409 GO:0007249 IGI acts_upstream_of I-kappaB kinase/NF-kappaB signaling 16260493 Process
26409 GO:0007252 IGI acts_upstream_of_or_within I-kappaB phosphorylation 16260493 Process
26409 GO:0007254 IDA involved_in JNK cascade 29291351 Process
26409 GO:0007254 IGI acts_upstream_of JNK cascade 16260493 Process
26409 GO:0016239 IMP involved_in positive regulation of macroautophagy 23778976 Process
26409 GO:0018107 IDA involved_in peptidyl-threonine phosphorylation 18762249 Process
26409 GO:0043123 IGI acts_upstream_of_or_within positive regulation of I-kappaB kinase/NF-kappaB signaling 16260493 Process
26409 GO:0043276 IMP involved_in anoikis 23778976 Process
26409 GO:0046330 IGI acts_upstream_of_or_within positive regulation of JNK cascade 16260493 Process
26409 GO:0060348 IMP involved_in bone development 20551513 Process
26409 GO:0060546 IMP involved_in negative regulation of necroptotic process 21052097 Process
26409 GO:0097190 IGI acts_upstream_of apoptotic signaling pathway 16260493 Process
26409 GO:0097190 IMP acts_upstream_of apoptotic signaling pathway 16260493 Process
26409 GO:1902443 IGI acts_upstream_of_or_within negative regulation of ripoptosome assembly involved in necroptotic process 21052097 Process
26409 GO:2000377 IMP acts_upstream_of_or_within regulation of reactive oxygen species metabolic process 21052097 Process
26409 GO:2000378 IMP involved_in negative regulation of reactive oxygen species metabolic process 21052097 Process
26409 GO:2001234 IGI acts_upstream_of_or_within negative regulation of apoptotic signaling pathway 16260493 Process
26409 GO:2001234 IMP acts_upstream_of_or_within negative regulation of apoptotic signaling pathway 16260493 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
26409 GO:0004674 IDA enables protein serine/threonine kinase activity 18762249 Function
26409 GO:0004708 IDA enables MAP kinase kinase activity 12464436 Function
26409 GO:0005515 IPI enables protein binding 12556533,17158449,17709393,18762249,19026643,19536134,19675569..... Function
26409 GO:0008349 IMP enables MAP kinase kinase kinase kinase activity 20551513 Function
26409 GO:0030971 IPI enables receptor tyrosine kinase binding 18762249 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
26409 GO:0014069 IDA located_in postsynaptic density 17114649 Component