Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:26419
  • Symbol:Mapk8
  • Description:mitogen-activated protein kinase 8

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
26419 GO:0001503 IMP acts_upstream_of_or_within ossification 15820682 Process
26419 GO:0001764 IMP involved_in neuron migration 21297631 Process
26419 GO:0006468 IDA acts_upstream_of_or_within protein phosphorylation 15767678,24889144 Process
26419 GO:0006468 IMP involved_in protein phosphorylation 22441692 Process
26419 GO:0007254 IDA involved_in JNK cascade 10811224 Process
26419 GO:0007258 IMP acts_upstream_of_or_within JUN phosphorylation 14967141 Process
26419 GO:0010468 IMP acts_upstream_of_or_within regulation of gene expression 19289495 Process
26419 GO:0018105 IDA acts_upstream_of_or_within peptidyl-serine phosphorylation 24889144 Process
26419 GO:0018105 IMP involved_in peptidyl-serine phosphorylation 29153991 Process
26419 GO:0018107 IMP acts_upstream_of_or_within peptidyl-threonine phosphorylation 14967141 Process
26419 GO:0031398 IMP involved_in positive regulation of protein ubiquitination 29153991 Process
26419 GO:0032436 IMP involved_in positive regulation of proteasomal ubiquitin-dependent protein catabolic process 29153991 Process
26419 GO:0042752 IMP involved_in regulation of circadian rhythm 22441692 Process
26419 GO:0046686 IGI acts_upstream_of_or_within response to cadmium ion 16458303 Process
26419 GO:0048813 IMP involved_in dendrite morphogenesis 16000625 Process
26419 GO:0050804 IDA involved_in modulation of chemical synaptic transmission 17284179 Process
26419 GO:0050804 IMP involved_in modulation of chemical synaptic transmission 17284179 Process
26419 GO:0061833 IMP acts_upstream_of_or_within protein localization to tricellular tight junction 24889144 Process
26419 GO:0070301 IDA acts_upstream_of_or_within cellular response to hydrogen peroxide 20808772 Process
26419 GO:0071216 IMP acts_upstream_of_or_within cellular response to biotic stimulus 23262141 Process
26419 GO:0071732 IMP acts_upstream_of_or_within cellular response to nitric oxide 18007661 Process
26419 GO:0071803 IMP acts_upstream_of_or_within positive regulation of podosome assembly 24127566 Process
26419 GO:0097190 IGI acts_upstream_of apoptotic signaling pathway 16458303 Process
26419 GO:0097300 IMP acts_upstream_of_or_within programmed necrotic cell death 18007661 Process
26419 GO:1900227 IDA involved_in positive regulation of NLRP3 inflammasome complex assembly 28943315 Process
26419 GO:2000017 IDA acts_upstream_of_or_within positive regulation of determination of dorsal identity 18316368 Process
26419 GO:2001235 IGI acts_upstream_of_or_within positive regulation of apoptotic signaling pathway 16458303 Process

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
26419 GO:0002102 IDA located_in podosome 24127566 Component
26419 GO:0005634 IDA located_in nucleus 15030387,15483136,24127566 Component
26419 GO:0005737 IDA located_in cytoplasm 15030387,24127566,29078390 Component
26419 GO:0005737 IMP located_in cytoplasm 29153991 Component
26419 GO:0005739 IDA located_in mitochondrion 11884367 Component
26419 GO:0005829 IDA located_in cytosol 11884367 Component
26419 GO:0030424 IMP located_in axon 22683681 Component
26419 GO:0043005 IDA located_in neuron projection 29078390 Component
26419 GO:0097441 IMP located_in basal dendrite 22683681 Component
26419 GO:0098685 IDA is_active_in Schaffer collateral - CA1 synapse 17284179 Component
26419 GO:0098685 IMP is_active_in Schaffer collateral - CA1 synapse 17284179 Component

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
26419 GO:0004672 IDA enables protein kinase activity 24889144 Function
26419 GO:0004674 IDA enables protein serine/threonine kinase activity 24127566,24889144,28943315 Function
26419 GO:0004705 IDA enables JUN kinase activity 10811224,15579909,19289495 Function
26419 GO:0004712 IMP enables protein serine/threonine/tyrosine kinase activity 29153991 Function
26419 GO:0005515 IPI enables protein binding 10471813,10523642,10581243,11279197,11562351,12855407,15483136..... Function
26419 GO:0016301 IDA enables kinase activity 12808090,15483136,15767678 Function