Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:2737
  • Symbol:GLI3
  • Description:GLI family zinc finger 3

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2737 GO:0000122 IDA acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II 10693759 Process
2737 GO:0000122 IDA involved_in negative regulation of transcription by RNA polymerase II 12435627,19084012 Process
2737 GO:0007224 IDA involved_in smoothened signaling pathway 31279575 Process
2737 GO:0035108 IMP involved_in limb morphogenesis 9354785,18478223 Process
2737 GO:0045892 IDA involved_in negative regulation of DNA-templated transcription 12435627,16254602,19084012 Process
2737 GO:0045944 IDA involved_in positive regulation of transcription by RNA polymerase II 17000779 Process
2737 GO:0045944 IMP involved_in positive regulation of transcription by RNA polymerase II 18559511 Process
2737 GO:0090090 IDA involved_in negative regulation of canonical Wnt signaling pathway 17331723 Process
2737 GO:1990787 IDA involved_in negative regulation of hh target transcription factor activity 24311597 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2737 GO:0000977 IDA enables RNA polymerase II transcription regulatory region sequence-specific DNA binding 18298960 Function
2737 GO:0000978 IDA enables RNA polymerase II cis-regulatory region sequence-specific DNA binding 2118997 Function
2737 GO:0003700 IDA enables DNA-binding transcription factor activity 10077605,17000779,17764085 Function
2737 GO:0005515 IPI enables protein binding 10564661,11238441,12435627,16371461,17000779,17764085,19389374..... Function
2737 GO:0008013 IPI enables beta-catenin binding 17331723 Function
2737 GO:0035035 IPI enables histone acetyltransferase binding 10075717 Function
2737 GO:0036033 IDA enables mediator complex binding 17000779 Function
2737 GO:0042826 IDA enables histone deacetylase binding 12435627 Function
2737 GO:1990837 IDA enables sequence-specific double-stranded DNA binding 28473536 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2737 GO:0005634 IDA located_in nucleus 10693759,11238441,12435627,16254602,18559511 Component
2737 GO:0005654 IDA located_in nucleoplasm Component
2737 GO:0005730 IDA located_in nucleolus Component
2737 GO:0005737 IDA located_in cytoplasm 10077605,11238441,12435627 Component
2737 GO:0005829 IDA located_in cytosol 18559511 Component
2737 GO:0005929 IDA located_in cilium 16254602,19592253 Component
2737 GO:0043231 IDA located_in intracellular membrane-bounded organelle Component
2737 GO:1990788 IPI part_of GLI-SUFU complex 24311597 Component