Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:28996
  • Symbol:HIPK2
  • Description:homeodomain interacting protein kinase 2

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
28996 GO:0003714 IDA enables transcription corepressor activity 12874272 Function
28996 GO:0004672 IDA enables protein kinase activity 19448668 Function
28996 GO:0004674 IDA enables protein serine/threonine kinase activity 33591310 Function
28996 GO:0005515 IPI enables protein binding 12220523,12874272,14647468,16917507,19448668,19820693,20940704..... Function
28996 GO:0046332 IPI enables SMAD binding 12874272 Function
28996 GO:0046790 IPI enables virion binding 14990717 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
28996 GO:0005634 IDA located_in nucleus 12220523,14647468,33591310 Component
28996 GO:0005654 IDA located_in nucleoplasm Component
28996 GO:0005737 IDA located_in cytoplasm 33591310 Component
28996 GO:0010494 IDA located_in cytoplasmic stress granule 33591310 Component
28996 GO:0016604 IDA located_in nuclear body 12874272,33591310 Component
28996 GO:0016605 IDA colocalizes_with PML body 14647468 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
28996 GO:0006468 IDA involved_in protein phosphorylation 19448668 Process
28996 GO:0006978 IDA involved_in DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator 14647468 Process
28996 GO:0018105 IDA involved_in peptidyl-serine phosphorylation 33591310 Process
28996 GO:0030511 IMP involved_in positive regulation of transforming growth factor beta receptor signaling pathway 14678985 Process
28996 GO:0030514 IMP involved_in negative regulation of BMP signaling pathway 12874272 Process
28996 GO:0045766 IDA involved_in positive regulation of angiogenesis 19046997 Process
28996 GO:0045893 IMP involved_in positive regulation of DNA-templated transcription 14647468 Process
28996 GO:0046330 IMP involved_in positive regulation of JNK cascade 14678985 Process
28996 GO:0060395 IDA involved_in SMAD protein signal transduction 12874272 Process
28996 GO:2000059 IMP involved_in negative regulation of ubiquitin-dependent protein catabolic process 21628596 Process