Gene Ontology

Gene Info

  • Species:Rat (Rattus norvegicus)
  • GeneID:29192
  • Symbol:Psen1
  • Description:presenilin 1

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
29192 GO:0003407 IEP involved_in neural retina development 12401445 Process
29192 GO:0006509 IMP involved_in membrane protein ectodomain proteolysis 17433308 Process
29192 GO:0016485 IDA involved_in protein processing 15456764 Process
29192 GO:0021549 IEP involved_in cerebellum development 16298244 Process
29192 GO:0043066 IDA involved_in negative regulation of apoptotic process 11895366 Process
29192 GO:0043524 IMP involved_in negative regulation of neuron apoptotic process 11895366 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
29192 GO:0004175 IDA enables endopeptidase activity 15456764 Function
29192 GO:0005515 IPI enables protein binding 12297508,15456764,22535952 Function
29192 GO:0008233 IDA enables peptidase activity 15456764 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
29192 GO:0005743 IDA located_in mitochondrial inner membrane 12099705 Component
29192 GO:0005765 IDA located_in lysosomal membrane 12736250 Component
29192 GO:0005769 IDA located_in early endosome 20126630 Component
29192 GO:0008021 IDA located_in synaptic vesicle 20126630 Component
29192 GO:0009986 IDA located_in cell surface 11570818 Component
29192 GO:0031594 IDA located_in neuromuscular junction 16595164 Component
29192 GO:0032991 IDA part_of protein-containing complex 15456764 Component
29192 GO:0042383 IDA located_in sarcolemma 16595164 Component
29192 GO:0042734 IDA is_active_in presynaptic membrane 20126630 Component
29192 GO:0097060 IDA located_in synaptic membrane 20126630 Component