Gene Ontology

Gene Info

  • Species:Rat (Rattus norvegicus)
  • GeneID:29290
  • Symbol:Adora1
  • Description:adenosine A1 receptor

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
29290 GO:0001609 IDA enables G protein-coupled adenosine receptor activity 9261808 Function
29290 GO:0001664 IPI enables G protein-coupled receptor binding 11390975,12417330 Function
29290 GO:0001883 IPI enables purine nucleoside binding 11906959 Function
29290 GO:0005515 IPI enables protein binding 11390975,19181933 Function
29290 GO:0031072 IPI enables heat shock protein binding 10866672 Function
29290 GO:0031683 IDA enables G-protein beta/gamma-subunit complex binding 12764156 Function
29290 GO:0032795 IDA enables heterotrimeric G-protein binding 12764156 Function
29290 GO:0044877 IPI enables protein-containing complex binding 16481441 Function
29290 GO:0046982 IPI enables protein heterodimerization activity 11390975 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
29290 GO:0001659 IMP involved_in temperature homeostasis 16352472 Process
29290 GO:0001666 IMP involved_in response to hypoxia 16690710 Process
29290 GO:0002087 IMP involved_in regulation of respiratory gaseous exchange by nervous system process 16352472 Process
29290 GO:0002674 IDA involved_in negative regulation of acute inflammatory response 2167912 Process
29290 GO:0002793 IMP involved_in positive regulation of peptide secretion 16286581 Process
29290 GO:0003084 IMP involved_in positive regulation of systemic arterial blood pressure 8998253 Process
29290 GO:0003085 IDA involved_in negative regulation of systemic arterial blood pressure 9597368 Process
29290 GO:0006612 IMP involved_in protein targeting to membrane 19879903 Process
29290 GO:0007186 IDA involved_in G protein-coupled receptor signaling pathway 12764156 Process
29290 GO:0007193 IMP involved_in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway 16286581 Process
29290 GO:0008285 IDA involved_in negative regulation of cell population proliferation 12021208 Process
29290 GO:0014050 IDA involved_in negative regulation of glutamate secretion 16481441 Process
29290 GO:0016042 IMP involved_in lipid catabolic process 19093734 Process
29290 GO:0032229 IDA NOT involved_in negative regulation of synaptic transmission, GABAergic 12626609 Process
29290 GO:0032229 IMP involved_in negative regulation of synaptic transmission, GABAergic 12626609 Process
29290 GO:0032244 IDA involved_in positive regulation of nucleoside transport 15024061 Process
29290 GO:0032900 IMP involved_in negative regulation of neurotrophin production 19524026 Process
29290 GO:0035307 IDA involved_in positive regulation of protein dephosphorylation 12234781 Process
29290 GO:0042311 IDA involved_in vasodilation 12100087 Process
29290 GO:0042321 IDA involved_in negative regulation of circadian sleep/wake cycle, sleep 16109808 Process
29290 GO:0042323 IMP involved_in negative regulation of circadian sleep/wake cycle, non-REM sleep 19491711 Process
29290 GO:0043066 IDA involved_in negative regulation of apoptotic process 12578815 Process
29290 GO:0043268 IDA involved_in positive regulation of potassium ion transport 9261808 Process
29290 GO:0043410 IDA involved_in positive regulation of MAPK cascade 12764156 Process
29290 GO:0045741 IMP involved_in positive regulation of epidermal growth factor-activated receptor activity 19574994 Process
29290 GO:0045776 IMP involved_in negative regulation of blood pressure 16690710 Process
29290 GO:0045777 IDA involved_in positive regulation of blood pressure 12234813 Process
29290 GO:0046888 IMP involved_in negative regulation of hormone secretion 15044554 Process
29290 GO:0050890 IMP involved_in cognition 19307960 Process
29290 GO:0050965 IMP involved_in detection of temperature stimulus involved in sensory perception of pain 20065990 Process
29290 GO:0050995 IDA involved_in negative regulation of lipid catabolic process 15220221 Process
29290 GO:0050996 IDA involved_in positive regulation of lipid catabolic process 9597368 Process
29290 GO:0051967 IDA involved_in negative regulation of synaptic transmission, glutamatergic 16481441 Process
29290 GO:0055089 IDA involved_in fatty acid homeostasis 15220221 Process
29290 GO:0055117 IMP involved_in regulation of cardiac muscle contraction 20334814 Process
29290 GO:0060079 IMP involved_in excitatory postsynaptic potential 19942300 Process
29290 GO:0070328 IDA involved_in triglyceride homeostasis 15220221 Process
29290 GO:0086004 IDA involved_in regulation of cardiac muscle cell contraction 19525381 Process
29290 GO:0099509 EXP involved_in regulation of presynaptic cytosolic calcium ion concentration 12963795 Process
29290 GO:0099509 IDA involved_in regulation of presynaptic cytosolic calcium ion concentration 12963795 Process
29290 GO:1900272 IMP involved_in negative regulation of long-term synaptic potentiation 14596853 Process

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
29290 GO:0016323 IDA located_in basolateral plasma membrane 15024061 Component
29290 GO:0030425 IDA located_in dendrite 12417330,16952160 Component
29290 GO:0030673 IDA located_in axolemma 16481441 Component
29290 GO:0032279 IDA located_in asymmetric synapse 16481441 Component
29290 GO:0042734 IDA is_active_in presynaptic membrane 16952160 Component
29290 GO:0042734 IDA located_in presynaptic membrane 16481441,16952160 Component
29290 GO:0043025 IDA located_in neuronal cell body 15044554 Component
29290 GO:0043195 IDA located_in terminal bouton 16952160 Component
29290 GO:0044297 IDA located_in cell body 12417330 Component
29290 GO:0044305 EXP is_active_in calyx of Held 12963795 Component
29290 GO:0044305 IDA is_active_in calyx of Held 12963795 Component
29290 GO:0045211 IDA is_active_in postsynaptic membrane 16952160 Component
29290 GO:0045211 IDA located_in postsynaptic membrane 16481441,16952160 Component
29290 GO:0048786 IDA located_in presynaptic active zone 16481441 Component