Gene Ontology

Gene Info

  • Species:Rat (Rattus norvegicus)
  • GeneID:29495
  • Symbol:Dlg4
  • Description:discs large MAGUK scaffold protein 4

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
29495 GO:0002091 IDA involved_in negative regulation of receptor internalization 11526121 Process
29495 GO:0007204 IMP involved_in positive regulation of cytosolic calcium ion concentration 20531396 Process
29495 GO:0021987 IEP involved_in cerebral cortex development 14597197 Process
29495 GO:0035418 IMP involved_in protein localization to synapse 12097487,15620359 Process
29495 GO:0048168 IMP involved_in regulation of neuronal synaptic plasticity 19596852 Process
29495 GO:0050775 IMP involved_in positive regulation of dendrite morphogenesis 25424568 Process
29495 GO:0050806 IDA involved_in positive regulation of synaptic transmission 12930820 Process
29495 GO:0051965 IMP involved_in positive regulation of synapse assembly 26738857 Process
29495 GO:0060997 IMP involved_in dendritic spine morphogenesis 21525273 Process
29495 GO:0061098 IMP involved_in positive regulation of protein tyrosine kinase activity 17526495 Process
29495 GO:0097061 IMP involved_in dendritic spine organization 26679993 Process
29495 GO:0097113 IMP involved_in AMPA glutamate receptor clustering 21525273 Process
29495 GO:0097120 IMP involved_in receptor localization to synapse 21525273 Process
29495 GO:0098970 IMP involved_in postsynaptic neurotransmitter receptor diffusion trapping 17329211 Process
29495 GO:0150012 IGI involved_in positive regulation of neuron projection arborization 25424568 Process
29495 GO:1904719 IMP involved_in positive regulation of AMPA glutamate receptor clustering 19596852 Process
29495 GO:2000310 IDA involved_in regulation of NMDA receptor activity 12930820 Process
29495 GO:2000310 IMP involved_in regulation of NMDA receptor activity 12930820,26679993 Process
29495 GO:2000463 IDA involved_in positive regulation of excitatory postsynaptic potential 12930820 Process
29495 GO:2000463 IMP involved_in positive regulation of excitatory postsynaptic potential 12930820 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
29495 GO:0005102 IPI enables signaling receptor binding 9808460,25424568 Function
29495 GO:0005109 IPI enables frizzled binding 25424568 Function
29495 GO:0005515 IPI enables protein binding 1127911,7569905,8601796,9115257,9694864,9756850,9786987,980846..... Function
29495 GO:0019894 IPI enables kinesin binding 12097473 Function
29495 GO:0019901 IPI enables protein kinase binding 20220006 Function
29495 GO:0019903 IPI enables protein phosphatase binding 20410104 Function
29495 GO:0030165 IMP enables PDZ domain binding 25424568 Function
29495 GO:0030165 IPI enables PDZ domain binding 10644767,15024025 Function
29495 GO:0031697 IPI enables beta-1 adrenergic receptor binding 11526121 Function
29495 GO:0031698 IPI enables beta-2 adrenergic receptor binding 20395454 Function
29495 GO:0031748 IPI enables D1 dopamine receptor binding 23041629 Function
29495 GO:0031812 IPI enables P2Y1 nucleotide receptor binding 20847060 Function
29495 GO:0033130 IDA enables acetylcholine receptor binding 22593058 Function
29495 GO:0035254 IPI enables glutamate receptor binding 20847060 Function
29495 GO:0035255 IPI enables ionotropic glutamate receptor binding 10414981,16540568,16606616,17270176 Function
29495 GO:0044877 IPI enables protein-containing complex binding 11178875,12618293,20197063,22843680 Function
29495 GO:0097109 IPI enables neuroligin family protein binding 11368788 Function
29495 GO:0097110 IPI enables scaffold protein binding 10939335 Function
29495 GO:0098919 IDA enables structural constituent of postsynaptic density 21525273 Function
29495 GO:0098919 IMP enables structural constituent of postsynaptic density 21525273 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
29495 GO:0005886 IDA colocalizes_with plasma membrane 20847060 Component
29495 GO:0005911 IDA located_in cell-cell junction 26595655 Component
29495 GO:0014069 IDA located_in postsynaptic density 1419001,11502259,17310244,21525273,24613359,26595655,27307232,..... Component
29495 GO:0016020 IDA located_in membrane 20089912 Component
29495 GO:0030425 IDA located_in dendrite 11931740,14597197,27307232 Component
29495 GO:0032839 IDA located_in dendrite cytoplasm 1419001 Component
29495 GO:0043197 IDA located_in dendritic spine 26679993,30021165 Component
29495 GO:0044224 IDA located_in juxtaparanode region of axon 19109503,20089912 Component
29495 GO:0044307 IDA located_in dendritic branch 20802490 Component
29495 GO:0045202 IDA located_in synapse 11483650,12097487,14642282,15657400,15681343 Component
29495 GO:0045202 IMP located_in synapse 27307232 Component
29495 GO:0045211 IDA colocalizes_with postsynaptic membrane 20847060 Component
29495 GO:0045211 IDA located_in postsynaptic membrane 11483650,26679993 Component
29495 GO:0060076 IDA located_in excitatory synapse 19730411 Component
29495 GO:0097060 IDA located_in synaptic membrane 10414981 Component
29495 GO:0098839 IDA is_active_in postsynaptic density membrane 20357126 Component
29495 GO:0098978 IDA is_active_in glutamatergic synapse 20357126,21525273 Component
29495 GO:0098978 IMP is_active_in glutamatergic synapse 21525273 Component
29495 GO:1990635 IDA located_in proximal dendrite 20802490 Component