Gene Ontology

Gene Info

• Species:Rat (Rattus norvegicus)
• GeneID:297893
• Symbol:Hdac1
• Description:histone deacetylase 1

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
297893	GO:0000785	IDA	part_of	chromatin	18271930	Component
297893	GO:0032991	IDA	part_of	protein-containing complex	10491605	Component
297893	GO:0048471	IDA	located_in	perinuclear region of cytoplasm	20037577	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
297893	GO:0001975	IMP	involved_in	response to amphetamine	18632938	Process
297893	GO:0008284	IMP	involved_in	positive regulation of cell population proliferation	21465537	Process
297893	GO:0008285	IDA	involved_in	negative regulation of cell population proliferation	18271930	Process
297893	GO:0009410	IEP	involved_in	response to xenobiotic stimulus	18550052	Process
297893	GO:0010628	IGI	involved_in	positive regulation of gene expression	28867608	Process
297893	GO:0031000	IEP	involved_in	response to caffeine	24717552	Process
297893	GO:0032496	IEP	involved_in	response to lipopolysaccharide	23271618,24595367	Process
297893	GO:0032732	IMP	involved_in	positive regulation of interleukin-1 production	22772764	Process
297893	GO:0032760	IMP	involved_in	positive regulation of tumor necrosis factor production	22772764	Process
297893	GO:0034599	IDA	involved_in	cellular response to oxidative stress	17600529	Process
297893	GO:0036120	IGI	involved_in	cellular response to platelet-derived growth factor stimulus	28867608	Process
297893	GO:0042531	IMP	involved_in	positive regulation of tyrosine phosphorylation of STAT protein	21465537	Process
297893	GO:0043524	IMP	involved_in	negative regulation of neuron apoptotic process	15769944	Process
297893	GO:0045892	IDA	involved_in	negative regulation of DNA-templated transcription	18271930	Process
297893	GO:0046676	IMP	involved_in	negative regulation of insulin secretion	22772764	Process
297893	GO:0048661	IGI	involved_in	positive regulation of smooth muscle cell proliferation	28867608	Process
297893	GO:0048714	IMP	involved_in	positive regulation of oligodendrocyte differentiation	22573687	Process
297893	GO:0055093	IEP	involved_in	response to hyperoxia	21905265	Process
297893	GO:0070932	IMP	involved_in	histone H3 deacetylation	19765194	Process
297893	GO:0071356	IEP	involved_in	cellular response to tumor necrosis factor	20037577	Process
297893	GO:2000343	IMP	involved_in	positive regulation of chemokine (C-X-C motif) ligand 2 production	22772764	Process
297893	GO:2000676	IMP	involved_in	positive regulation of type B pancreatic cell apoptotic process	22772764	Process
297893	GO:2000757	IMP	involved_in	negative regulation of peptidyl-lysine acetylation	21465537	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
297893	GO:0003682	IDA	enables	chromatin binding	23671328	Function
297893	GO:0004407	IMP	enables	histone deacetylase activity	19765194	Function
297893	GO:0005515	IPI	enables	protein binding	17353261,18413351,23671328	Function
297893	GO:0019213	IDA	enables	deacetylase activity	23868068	Function
297893	GO:0044877	IDA	enables	protein-containing complex binding	18271930	Function
297893	GO:0140297	IPI	enables	DNA-binding transcription factor binding	18255031	Function