Gene Ontology

Gene Info

• Species:Rat (Rattus norvegicus)
• GeneID:299858
• Symbol:Lrp1
• Description:LDL receptor related protein 1

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
299858	GO:0002020	IPI	enables	protease binding	10514495	Function
299858	GO:0005515	IPI	enables	protein binding	12153398,16303771,23132925	Function
299858	GO:0015026	IDA	enables	coreceptor activity	18321860	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
299858	GO:0005768	IDA	located_in	endosome	14701798	Component
299858	GO:0030136	IDA	located_in	clathrin-coated vesicle	16190982	Component
299858	GO:0030425	IDA	located_in	dendrite	9046007	Component
299858	GO:0032593	IDA	located_in	insulin-responsive compartment	19864425	Component
299858	GO:0043025	IDA	located_in	neuronal cell body	9046007	Component
299858	GO:0044295	IDA	located_in	axonal growth cone	26598525	Component
299858	GO:0045177	IDA	located_in	apical part of cell	20488202	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
299858	GO:0006898	IMP	involved_in	receptor-mediated endocytosis	8626514,18285446	Process
299858	GO:0007204	IMP	involved_in	positive regulation of cytosolic calcium ion concentration	18321860	Process
299858	GO:0007205	IMP	involved_in	protein kinase C-activating G protein-coupled receptor signaling pathway	17314289	Process
299858	GO:0010812	IMP	involved_in	negative regulation of cell-substrate adhesion	20197276	Process
299858	GO:0010976	IMP	involved_in	positive regulation of neuron projection development	24086544	Process
299858	GO:0010977	IMP	involved_in	negative regulation of neuron projection development	23132925	Process
299858	GO:0021987	IEP	involved_in	cerebral cortex development	8930375	Process
299858	GO:0035774	IMP	involved_in	positive regulation of insulin secretion involved in cellular response to glucose stimulus	24865476	Process
299858	GO:0043066	IMP	involved_in	negative regulation of apoptotic process	17065459	Process
299858	GO:0043524	IDA	involved_in	negative regulation of neuron apoptotic process	24086544	Process
299858	GO:0043524	IMP	involved_in	negative regulation of neuron apoptotic process	17314289	Process
299858	GO:0044242	IMP	involved_in	cellular lipid catabolic process	26506094	Process
299858	GO:0045773	IMP	involved_in	positive regulation of axon extension	21040802	Process
299858	GO:0048691	IDA	involved_in	positive regulation of axon extension involved in regeneration	23867460	Process
299858	GO:0048694	IDA	involved_in	positive regulation of collateral sprouting of injured axon	23867460	Process
299858	GO:0050766	IMP	involved_in	positive regulation of phagocytosis	19299462	Process
299858	GO:0051222	IMP	involved_in	positive regulation of protein transport	11100124	Process
299858	GO:0051481	IMP	involved_in	negative regulation of cytosolic calcium ion concentration	22674573	Process
299858	GO:0051895	IMP	involved_in	negative regulation of focal adhesion assembly	20197276	Process
299858	GO:0061642	IMP	involved_in	chemoattraction of axon	26598525	Process
299858	GO:0070374	IMP	involved_in	positive regulation of ERK1 and ERK2 cascade	24865476	Process
299858	GO:1900149	IMP	involved_in	positive regulation of Schwann cell migration	20197276	Process
299858	GO:1904109	IMP	involved_in	positive regulation of cholesterol import	22454363	Process
299858	GO:1904754	IMP	involved_in	positive regulation of vascular associated smooth muscle cell migration	20940000	Process
299858	GO:2000343	IMP	involved_in	positive regulation of chemokine (C-X-C motif) ligand 2 production	21290408	Process