Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:3065
  • Symbol:HDAC1
  • Description:histone deacetylase 1

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3065 GO:0000118 IDA part_of histone deacetylase complex 9651585 Component
3065 GO:0000785 HDA part_of chromatin 16217013 Component
3065 GO:0000785 IDA part_of chromatin 16731528,22926524,23629966,23770133 Component
3065 GO:0005634 IDA located_in nucleus 9651585,10846170,18347167,18936100,20523938,28977666,33283408..... Component
3065 GO:0005654 IDA located_in nucleoplasm 22720776,22926524 Component
3065 GO:0005829 IDA located_in cytosol 18326024 Component
3065 GO:0016580 IDA part_of Sin3 complex 17827154 Component
3065 GO:0016581 IDA part_of NuRD complex 17827154,19644445,22926524,33283408 Component
3065 GO:0032991 HDA part_of protein-containing complex 16217013 Component
3065 GO:0032991 IDA part_of protein-containing complex 28046085 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3065 GO:0000122 IDA involved_in negative regulation of transcription by RNA polymerase II 18854353,30599067 Process
3065 GO:0000122 IGI involved_in negative regulation of transcription by RNA polymerase II 18936100,23770133 Process
3065 GO:0000122 IMP involved_in negative regulation of transcription by RNA polymerase II 18850004 Process
3065 GO:0006338 HDA involved_in chromatin remodeling 16217013 Process
3065 GO:0006338 IDA involved_in chromatin remodeling 9790534 Process
3065 GO:0006346 IGI involved_in DNA methylation-dependent heterochromatin formation 23770133 Process
3065 GO:0006357 IGI involved_in regulation of transcription by RNA polymerase II 19057576 Process
3065 GO:0006476 IDA involved_in protein deacetylation 23629966 Process
3065 GO:0008284 IMP involved_in positive regulation of cell population proliferation 18347167 Process
3065 GO:0010629 IMP involved_in negative regulation of gene expression 16581785 Process
3065 GO:0010832 IMP NOT involved_in negative regulation of myotube differentiation 10983972 Process
3065 GO:0016575 IDA involved_in histone deacetylation 10444591 Process
3065 GO:0043922 IMP involved_in negative regulation by host of viral transcription 16540471 Process
3065 GO:0045892 IMP involved_in negative regulation of DNA-templated transcription 18247378,18974119 Process
3065 GO:0045893 IDA involved_in positive regulation of DNA-templated transcription 16762839 Process
3065 GO:0045944 IDA involved_in positive regulation of transcription by RNA polymerase II 16762839 Process
3065 GO:0052548 IMP involved_in regulation of endopeptidase activity 19057576 Process
3065 GO:0060766 IDA involved_in negative regulation of androgen receptor signaling pathway 15919722 Process
3065 GO:0070932 IDA involved_in histone H3 deacetylation 12590135 Process
3065 GO:0070933 IDA involved_in histone H4 deacetylation 12590135 Process
3065 GO:0090090 IGI involved_in negative regulation of canonical Wnt signaling pathway 18936100 Process
3065 GO:2000273 IMP acts_upstream_of positive regulation of signaling receptor activity 18316616 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3065 GO:0000978 IGI enables RNA polymerase II cis-regulatory region sequence-specific DNA binding 18974119 Function
3065 GO:0000979 IDA enables RNA polymerase II core promoter sequence-specific DNA binding 19057576 Function
3065 GO:0001046 IDA enables core promoter sequence-specific DNA binding 23629966 Function
3065 GO:0001222 IPI enables transcription corepressor binding 10898795 Function
3065 GO:0002039 IPI enables p53 binding 23629966 Function
3065 GO:0003714 IDA enables transcription corepressor activity 15919722,30599067 Function
3065 GO:0004407 IDA enables histone deacetylase activity 16762839,28497810 Function
3065 GO:0004407 IMP enables histone deacetylase activity 17996965,19182791 Function
3065 GO:0005515 IDA enables protein binding 17150957 Function
3065 GO:0005515 IPI enables protein binding 9150135,9468139,9468140,9651585,10220385,10779361,10846170,110..... Function
3065 GO:0019899 IPI enables enzyme binding 11062478,11136718,11641274 Function
3065 GO:0031492 HDA contributes_to nucleosomal DNA binding 16217013 Function
3065 GO:0033558 IDA enables protein lysine deacetylase activity 17172643,23629966 Function
3065 GO:0033558 IMP enables protein lysine deacetylase activity 19182791 Function
3065 GO:0042826 IPI enables histone deacetylase binding 12590135,28046085 Function
3065 GO:0051059 IPI enables NF-kappaB binding 17785205 Function
3065 GO:0061629 IPI enables RNA polymerase II-specific DNA-binding transcription factor binding 18850004,18936100,22926524 Function
3065 GO:0140297 IPI enables DNA-binding transcription factor binding 15509593,16731528,18974119,20590529 Function
3065 GO:0160009 IDA enables histone decrotonylase activity 28497810 Function