Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:3084
  • Symbol:NRG1
  • Description:neuregulin 1

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3084 GO:0003222 IDA involved_in ventricular trabecula myocardium morphogenesis 17336907 Process
3084 GO:0008284 IMP involved_in positive regulation of cell population proliferation 20682778 Process
3084 GO:0031334 IDA involved_in positive regulation of protein-containing complex assembly 10559227 Process
3084 GO:0032148 IMP involved_in activation of protein kinase B activity 20682778 Process
3084 GO:0038127 IDA involved_in ERBB signaling pathway 11389077 Process
3084 GO:0038127 IMP involved_in ERBB signaling pathway 20682778 Process
3084 GO:0038129 IDA involved_in ERBB3 signaling pathway 27353365 Process
3084 GO:0038130 IDA involved_in ERBB4 signaling pathway 28822966 Process
3084 GO:0038133 IDA involved_in ERBB2-ERBB3 signaling pathway 8702723 Process
3084 GO:0038135 IDA involved_in ERBB2-ERBB4 signaling pathway 19632177 Process
3084 GO:0038138 IDA involved_in ERBB4-ERBB4 signaling pathway 8702723,28822966 Process
3084 GO:0045892 IDA acts_upstream_of_or_within negative regulation of DNA-templated transcription 15073182 Process
3084 GO:0051048 IDA involved_in negative regulation of secretion 10559227 Process
3084 GO:0060379 IDA involved_in cardiac muscle cell myoblast differentiation 17336907 Process
3084 GO:0060956 IDA involved_in endocardial cell differentiation 17336907 Process
3084 GO:0070374 IMP involved_in positive regulation of ERK1 and ERK2 cascade 20682778 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3084 GO:0003712 IDA enables transcription coregulator activity 15073182 Function
3084 GO:0005178 IDA enables integrin binding 20682778 Function
3084 GO:0030296 IDA enables protein tyrosine kinase activator activity 8702723,19632177 Function
3084 GO:0043125 IDA enables ErbB-3 class receptor binding 20682778 Function
3084 GO:0048018 IDA enables receptor ligand activity 8702723,19632177,28822966 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3084 GO:0005615 IDA is_active_in extracellular space 8702723,19632177,28822966 Component
3084 GO:0005654 IDA located_in nucleoplasm Component