Gene Ontology

Gene Info

• Species:Human (Homo sapiens)
• GeneID:326
• Symbol:AIRE
• Description:autoimmune regulator

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
326	GO:0000977	IDA	enables	RNA polymerase II transcription regulatory region sequence-specific DNA binding	11533054	Function
326	GO:0003682	IDA	enables	chromatin binding	18292755	Function
326	GO:0005515	IPI	enables	protein binding	17474147,18292755,20085707,20185822	Function
326	GO:0008270	IDA	enables	zinc ion binding	19446523	Function
326	GO:0042393	IDA	enables	histone binding	18292755,19446523	Function
326	GO:0042802	IPI	enables	identical protein binding	15712268,20185822,28540407	Function

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
326	GO:0002509	IMP	involved_in	central tolerance induction to self antigen	26084028	Process
326	GO:0006355	IDA	involved_in	regulation of DNA-templated transcription	18292755	Process
326	GO:0045893	IDA	involved_in	positive regulation of DNA-templated transcription	18292755	Process
326	GO:0045893	IMP	involved_in	positive regulation of DNA-templated transcription	26084028	Process
326	GO:0045944	IMP	involved_in	positive regulation of transcription by RNA polymerase II	11274163	Process