Gene Ontology

Gene Info

• Species:Human (Homo sapiens)
• GeneID:3358
• Symbol:HTR2C
• Description:5-hydroxytryptamine receptor 2C

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
3358	GO:0001587	IDA	enables	Gq/11-coupled serotonin receptor activity	18703043	Function
3358	GO:0004993	IDA	enables	G protein-coupled serotonin receptor activity	7582481,12970106	Function
3358	GO:0005515	IPI	enables	protein binding	14988405,25770211,28258217,28514442,30157263,32296183.....	Function
3358	GO:0042802	IPI	enables	identical protein binding	15518545,16195233,25770211,28258217	Function
3358	GO:0051378	IDA	enables	serotonin binding	7582481,12970106,15831837,18703043,19057895	Function
3358	GO:0071886	IDA	enables	1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding	19057895	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
3358	GO:0005886	IDA	located_in	plasma membrane	12970106,18703043	Component
3358	GO:0005886	IMP	located_in	plasma membrane	18703043	Component
3358	GO:0098666	IDA	part_of	G protein-coupled serotonin receptor complex	12970106,18703043	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
3358	GO:0006874	IDA	involved_in	intracellular calcium ion homeostasis	19057895	Process
3358	GO:0007208	IDA	involved_in	phospholipase C-activating serotonin receptor signaling pathway	12970106	Process
3358	GO:0010513	IDA	involved_in	positive regulation of phosphatidylinositol biosynthetic process	19057895	Process
3358	GO:0019934	IDA	involved_in	cGMP-mediated signaling	12970106	Process
3358	GO:0051209	IMP	involved_in	release of sequestered calcium ion into cytosol	18703043	Process
3358	GO:0070374	IDA	involved_in	positive regulation of ERK1 and ERK2 cascade	19057895	Process
3358	GO:0098664	IDA	involved_in	G protein-coupled serotonin receptor signaling pathway	18703043	Process