Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:3579
  • Symbol:CXCR2
  • Description:C-X-C motif chemokine receptor 2

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3579 GO:0004918 IDA enables interleukin-8 receptor activity 10820279 Function
3579 GO:0004930 IDA enables G protein-coupled receptor activity 10438939 Function
3579 GO:0005515 IPI enables protein binding 17435771,21876773,22904195,23597562,32296183 Function
3579 GO:0016494 IDA enables C-X-C chemokine receptor activity 10878382 Function
3579 GO:0019959 IPI enables interleukin-8 binding 1840701 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3579 GO:0005654 IDA located_in nucleoplasm Component
3579 GO:0005886 IDA located_in plasma membrane Component
3579 GO:0009986 IDA located_in cell surface 10878382 Component
3579 GO:0015630 IDA located_in microtubule cytoskeleton Component
3579 GO:0016020 IDA located_in membrane 10725748 Component
3579 GO:0042629 IDA located_in mast cell granule 9725262 Component
3579 GO:0072686 IDA located_in mitotic spindle Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3579 GO:0006935 IDA involved_in chemotaxis 10725748 Process
3579 GO:0006968 IDA involved_in cellular defense response 10725748 Process
3579 GO:0007166 IDA involved_in cell surface receptor signaling pathway 10734056,10878382 Process
3579 GO:0007200 IDA involved_in phospholipase C-activating G protein-coupled receptor signaling pathway 10438939 Process
3579 GO:0008284 IDA involved_in positive regulation of cell population proliferation 10438939 Process
3579 GO:0030593 IDA involved_in neutrophil chemotaxis 10820279 Process
3579 GO:0031623 IDA involved_in receptor internalization 10734056 Process
3579 GO:0038112 IDA involved_in interleukin-8-mediated signaling pathway 10820279 Process
3579 GO:0042119 IDA involved_in neutrophil activation 10878382 Process