Gene Ontology

Gene Info

• Species:Fly (Drosophila melanogaster)
• GeneID:3772180
• Symbol:Sxl
• Description:Sex lethal

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
3772180	GO:0000381	IDA	involved_in	regulation of alternative mRNA splicing, via spliceosome	19727396,28675155	Process
3772180	GO:0007446	IMP	involved_in	imaginal disc growth	16207758	Process
3772180	GO:0009994	IDA	involved_in	oocyte differentiation	17067567	Process
3772180	GO:0017148	IDA	involved_in	negative regulation of translation	16122421	Process
3772180	GO:0019099	IMP	involved_in	female germ-line sex determination	35385723	Process
3772180	GO:0030237	IMP	involved_in	female sex determination	28675155	Process
3772180	GO:0033120	IDA	involved_in	positive regulation of RNA splicing	30590805	Process
3772180	GO:0045880	IDA	involved_in	positive regulation of smoothened signaling pathway	16207758	Process
3772180	GO:0045947	IMP	involved_in	negative regulation of translational initiation	16452508	Process
3772180	GO:0048142	IMP	involved_in	germarium-derived cystoblast division	29845608	Process
3772180	GO:0050821	IDA	involved_in	protein stabilization	16207758	Process
3772180	GO:1990399	IMP	involved_in	epithelium regeneration	26887495	Process
3772180	GO:2000035	IMP	involved_in	regulation of stem cell division	26887495	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
3772180	GO:0000900	IDA	enables	mRNA regulatory element binding translation repressor activity	16452508,16452509	Function
3772180	GO:0003723	IDA	enables	RNA binding	30590805	Function
3772180	GO:0003730	IDA	enables	mRNA 3'-UTR binding	16122421,25209665	Function
3772180	GO:0003730	IPI	enables	mRNA 3'-UTR binding	16452508	Function
3772180	GO:0005515	IPI	enables	protein binding	10521666,11526072,14597576,17284519,19013444	Function
3772180	GO:0008187	IDA	enables	poly-pyrimidine tract binding	10617208	Function
3772180	GO:0008266	IDA	enables	poly(U) RNA binding	10864047	Function
3772180	GO:0036002	IDA	enables	pre-mRNA binding	28675155	Function
3772180	GO:0048027	IDA	enables	mRNA 5'-UTR binding	16122421,25209665	Function
3772180	GO:0048027	IPI	enables	mRNA 5'-UTR binding	16452508	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
3772180	GO:0005737	IDA	located_in	cytoplasm	22645327	Component
3772180	GO:0032991	IPI	part_of	protein-containing complex	19013444	Component
3772180	GO:1990124	IPI	part_of	messenger ribonucleoprotein complex	16452508,16452509	Component