Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:3784
  • Symbol:KCNQ1
  • Description:potassium voltage-gated channel subfamily Q member 1

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3784 GO:0005249 IDA contributes_to voltage-gated potassium channel activity 16002409 Function
3784 GO:0005249 IDA enables voltage-gated potassium channel activity 8900283,17289006,24595108,24855057 Function
3784 GO:0005251 IDA contributes_to delayed rectifier potassium channel activity 8900283,9354802,10400998,11299204,19646991 Function
3784 GO:0005251 IDA enables delayed rectifier potassium channel activity 12522251,24184248,24269949,25037568 Function
3784 GO:0005515 IPI enables protein binding 19521339,19687231,20533308,22024150,23529131,24595108..... Function
3784 GO:0005516 IDA enables calmodulin binding 18165683 Function
3784 GO:0005546 IDA enables phosphatidylinositol-4,5-bisphosphate binding 25037568 Function
3784 GO:0008157 IDA enables protein phosphatase 1 binding 11799244 Function
3784 GO:0015271 IDA enables outward rectifier potassium channel activity 9312006,11101505,25705178 Function
3784 GO:0034236 IDA enables protein kinase A catalytic subunit binding 11799244 Function
3784 GO:0034237 IDA enables protein kinase A regulatory subunit binding 11799244 Function
3784 GO:0044325 IPI enables transmembrane transporter binding 11101505,12324418,20196769,24855057,25037568 Function
3784 GO:0086008 IMP enables voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 12522251 Function
3784 GO:0086089 IMP enables voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization 12522251,25786344 Function
3784 GO:0097110 IPI enables scaffold protein binding 11799244,16002409,18093912 Function
3784 GO:1902282 IMP enables voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 8528244 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3784 GO:0005737 IDA located_in cytoplasm 25037568 Component
3784 GO:0005764 IDA located_in lysosome 21957902 Component
3784 GO:0005769 IDA located_in early endosome 21957902 Component
3784 GO:0005769 IMP colocalizes_with early endosome 23529131 Component
3784 GO:0005770 IDA located_in late endosome 21957902 Component
3784 GO:0005783 IDA located_in endoplasmic reticulum 21228319,24855057 Component
3784 GO:0005783 IPI colocalizes_with endoplasmic reticulum 24855057 Component
3784 GO:0005886 IDA located_in plasma membrane 10646604,21228319,22024150,23529131,24184248,25037568,25705178..... Component
3784 GO:0008076 IDA part_of voltage-gated potassium channel complex 16002409,17289006,19646991 Component
3784 GO:0008076 IPI part_of voltage-gated potassium channel complex 25441029 Component
3784 GO:0016323 IDA located_in basolateral plasma membrane 21228319,21957902 Component
3784 GO:0034702 IPI part_of monoatomic ion channel complex 24855057 Component
3784 GO:0045121 IDA located_in membrane raft 20533308,24855057 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3784 GO:0010460 IMP involved_in positive regulation of heart rate 19646991 Process
3784 GO:0060048 IMP involved_in cardiac muscle contraction 8528244 Process
3784 GO:0060306 IDA involved_in regulation of membrane repolarization 11299204 Process
3784 GO:0060306 IMP involved_in regulation of membrane repolarization 8900283 Process
3784 GO:0060307 IMP involved_in regulation of ventricular cardiac muscle cell membrane repolarization 8528244 Process
3784 GO:0060372 IMP involved_in regulation of atrial cardiac muscle cell membrane repolarization 12522251 Process
3784 GO:0060452 IMP involved_in positive regulation of cardiac muscle contraction 19646991 Process
3784 GO:0071320 IDA involved_in cellular response to cAMP 11299204,16002409 Process
3784 GO:0071320 IMP involved_in cellular response to cAMP 18093912 Process
3784 GO:0071466 IDA involved_in cellular response to xenobiotic stimulus 9108097 Process
3784 GO:0071805 IDA involved_in potassium ion transmembrane transport 9354802,11299204,16002409,16556866 Process
3784 GO:0086005 IMP involved_in ventricular cardiac muscle cell action potential 8528244 Process
3784 GO:0086011 IDA involved_in membrane repolarization during action potential 8900283,11299204,19646991 Process
3784 GO:0086013 IMP involved_in membrane repolarization during cardiac muscle cell action potential 8528244 Process
3784 GO:0086014 IMP involved_in atrial cardiac muscle cell action potential 12522251 Process
3784 GO:0086091 IMP involved_in regulation of heart rate by cardiac conduction 8528244 Process
3784 GO:0097623 IDA involved_in potassium ion export across plasma membrane 8900283,10400998,17289006 Process
3784 GO:0098914 IMP involved_in membrane repolarization during atrial cardiac muscle cell action potential 12522251,25786344 Process
3784 GO:0098915 IMP involved_in membrane repolarization during ventricular cardiac muscle cell action potential 8528244 Process
3784 GO:1901381 IDA involved_in positive regulation of potassium ion transmembrane transport 8900283 Process