Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:3815
  • Symbol:KIT
  • Description:KIT proto-oncogene, receptor tyrosine kinase

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3815 GO:0001650 IDA located_in fibrillar center Component
3815 GO:0005615 IDA located_in extracellular space 14625290 Component
3815 GO:0005886 IDA located_in plasma membrane Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3815 GO:0002551 IDA involved_in mast cell chemotaxis 20100931 Process
3815 GO:0008584 IEP involved_in male gonad development 17848411 Process
3815 GO:0019221 IDA involved_in cytokine-mediated signaling pathway 21640708 Process
3815 GO:0030036 IDA involved_in actin cytoskeleton organization 1721869 Process
3815 GO:0032765 IDA involved_in positive regulation of mast cell cytokine production 20100931 Process
3815 GO:0038093 IDA involved_in Fc receptor signaling pathway 20100931 Process
3815 GO:0038109 IDA involved_in Kit signaling pathway 17662946 Process
3815 GO:0042531 IMP involved_in positive regulation of tyrosine phosphorylation of STAT protein 21135090 Process
3815 GO:0043303 IMP involved_in mast cell degranulation 20100931 Process
3815 GO:0043410 IMP involved_in positive regulation of MAPK cascade 21640708 Process
3815 GO:0046427 IMP involved_in positive regulation of receptor signaling pathway via JAK-STAT 21135090 Process
3815 GO:0046777 IDA involved_in protein autophosphorylation 21640708 Process
3815 GO:0051091 IMP involved_in positive regulation of DNA-binding transcription factor activity 21135090 Process
3815 GO:0060326 IDA involved_in cell chemotaxis 1721869 Process
3815 GO:1905065 IDA involved_in positive regulation of vascular associated smooth muscle cell differentiation 19088079 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3815 GO:0004714 IDA enables transmembrane receptor protein tyrosine kinase activity 21640708 Function
3815 GO:0005515 IPI enables protein binding 1382595,7523381,7537096,10377264,10397721,11018522,12878163,17..... Function
3815 GO:0019955 IDA enables cytokine binding 21640708 Function
3815 GO:0042803 IPI enables protein homodimerization activity 21640708 Function