Gene Ontology

Gene Info

  • Species:Fly (Drosophila melanogaster)
  • GeneID:39659
  • Symbol:Tak1
  • Description:TGF-beta activated kinase 1

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
39659 GO:0004674 IDA enables protein serine/threonine kinase activity 28377500,35905720 Function
39659 GO:0004706 IMP enables JUN kinase kinase kinase activity 14519762 Function
39659 GO:0004709 IMP enables MAP kinase kinase kinase activity 10757786 Function
39659 GO:0005515 IPI enables protein binding 23532117 Function
39659 GO:0031625 IPI enables ubiquitin protein ligase binding 16179944 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
39659 GO:0005737 IDA located_in cytoplasm 24429281 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
39659 GO:0006915 IGI involved_in apoptotic process 10757786 Process
39659 GO:0006955 IMP involved_in immune response 14519762 Process
39659 GO:0007249 IMP involved_in I-kappaB kinase/NF-kappaB signaling 14519762 Process
39659 GO:0007254 IGI involved_in JNK cascade 10757786 Process
39659 GO:0007391 IMP involved_in dorsal closure 10757786 Process
39659 GO:0010506 IMP involved_in regulation of autophagy 23532117 Process
39659 GO:0010628 IMP involved_in positive regulation of gene expression 25737837 Process
39659 GO:0016318 IMP involved_in ommatidial rotation 11287182 Process
39659 GO:0033209 IGI involved_in tumor necrosis factor-mediated signaling pathway 12065414,16079232,19223855,23726905,25874673,31409797..... Process
39659 GO:0033209 IMP involved_in tumor necrosis factor-mediated signaling pathway 17765686,20933214,22065747,24162658,30847993 Process
39659 GO:0043068 IGI acts_upstream_of positive regulation of programmed cell death 12065414,16079232,19223855,25874673,31409797 Process
39659 GO:0043068 IMP acts_upstream_of positive regulation of programmed cell death 17765686,22065747,24162658,30847993 Process
39659 GO:0046330 IGI involved_in positive regulation of JNK cascade 23726905 Process
39659 GO:0046330 IMP involved_in positive regulation of JNK cascade 14519762,16451733 Process
39659 GO:0048749 IMP involved_in compound eye development 10757786 Process
39659 GO:0048802 IMP involved_in notum morphogenesis 11287182 Process
39659 GO:0050829 IGI involved_in defense response to Gram-negative bacterium 17129215 Process
39659 GO:0050829 IMP involved_in defense response to Gram-negative bacterium 16894030,22549468 Process
39659 GO:0051607 IMP involved_in defense response to virus 19829691,35905720 Process
39659 GO:0061057 IGI involved_in peptidoglycan recognition protein signaling pathway 16081424,16763552,35911722 Process
39659 GO:0061057 IMP involved_in peptidoglycan recognition protein signaling pathway 12431377,14519762,16894030,17343912,19497884,20122400,22549468..... Process
39659 GO:0071222 IMP involved_in cellular response to lipopolysaccharide 16451733 Process
39659 GO:0090175 IGI involved_in regulation of establishment of planar polarity 29758044 Process