Gene Ontology

Gene Info

• Species:Human (Homo sapiens)
• GeneID:4000
• Symbol:LMNA
• Description:lamin A/C

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
4000	GO:0005515	IPI	enables	protein binding	10514485,10727209,11587540,11801724,14597414,15140953,15161933.....	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
4000	GO:0005634	HDA	located_in	nucleus	16791210	Component
4000	GO:0005634	IDA	located_in	nucleus	18809582,20810912	Component
4000	GO:0005635	IDA	located_in	nuclear envelope	18606848,27534416	Component
4000	GO:0005635	IMP	colocalizes_with	nuclear envelope	21610090	Component
4000	GO:0005654	IDA	located_in	nucleoplasm	27534416	Component
4000	GO:0016363	IDA	located_in	nuclear matrix	31548606	Component
4000	GO:0016607	IDA	located_in	nuclear speck		Component
4000	GO:0031965	HDA	located_in	nuclear membrane	16791210	Component
4000	GO:0035861	IDA	located_in	site of double-strand break	31548606	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
4000	GO:0008285	IMP	involved_in	negative regulation of cell population proliferation	27534416	Process
4000	GO:0071456	IEP	involved_in	cellular response to hypoxia	20810912	Process
4000	GO:0090398	IDA	acts_upstream_of_or_within_positive_effect	cellular senescence	20458013	Process
4000	GO:1990683	IDA	involved_in	DNA double-strand break attachment to nuclear envelope	31548606	Process