Gene Ontology

Gene Info

  • Species:Fly (Drosophila melanogaster)
  • GeneID:40090
  • Symbol:fz2
  • Description:frizzled 2

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
40090 GO:0005634 IDA located_in nucleus 24046358 Component
40090 GO:0005769 IDA colocalizes_with early endosome 16530179 Component
40090 GO:0005770 IDA colocalizes_with late endosome 16530179 Component
40090 GO:0005886 IDA located_in plasma membrane 8717036,15514021,16530179 Component
40090 GO:1990909 IDA part_of Wnt signalosome 12711303 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
40090 GO:0007367 IGI involved_in segment polarity determination 10457026,10556068,12636921,16163385 Process
40090 GO:0007435 IMP involved_in salivary gland morphogenesis 17507403 Process
40090 GO:0007494 IGI involved_in midgut development 10457026 Process
40090 GO:0008045 IMP involved_in motor neuron axon guidance 17764943 Process
40090 GO:0008585 IMP involved_in female gonad development 11970894 Process
40090 GO:0008587 IGI involved_in imaginal disc-derived wing margin morphogenesis 10556068 Process
40090 GO:0008587 IMP involved_in imaginal disc-derived wing margin morphogenesis 9671581 Process
40090 GO:0016055 IDA involved_in Wnt signaling pathway 8717036 Process
40090 GO:0016201 IMP involved_in synaptic target inhibition 17764943 Process
40090 GO:0016477 IMP involved_in cell migration 11970894 Process
40090 GO:0031290 IMP involved_in retinal ganglion cell axon guidance 16369482 Process
40090 GO:0035206 IMP involved_in regulation of hemocyte proliferation 20688956 Process
40090 GO:0035293 IGI involved_in chitin-based larval cuticle pattern formation 16163385 Process
40090 GO:0042685 IGI involved_in cardioblast cell fate specification 10457026 Process
40090 GO:0048665 IGI involved_in neuron fate specification 10457026 Process
40090 GO:0048675 IMP involved_in axon extension 17032066 Process
40090 GO:0050770 IMP involved_in regulation of axonogenesis 24303071 Process
40090 GO:0050808 IPI involved_in synapse organization 16682643 Process
40090 GO:0060070 IDA involved_in canonical Wnt signaling pathway 8717036,12729465,15459103 Process
40090 GO:0060070 IGI involved_in canonical Wnt signaling pathway 10457026,10556068,12636921,16163385 Process
40090 GO:0060070 IMP involved_in canonical Wnt signaling pathway 9671581,17433287 Process
40090 GO:0060250 IMP involved_in germ-line stem-cell niche homeostasis 26452202 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
40090 GO:0017147 IDA enables Wnt-protein binding 8717036 Function
40090 GO:0017147 IPI enables Wnt-protein binding 12205098,16291792,22285813 Function
40090 GO:0030165 IPI enables PDZ domain binding 16682643 Function
40090 GO:0042813 IDA enables Wnt receptor activity 8717036,15459103,16530179 Function
40090 GO:0042813 IGI enables Wnt receptor activity 12729465 Function