Gene Ontology

Gene Info

• Species:Human (Homo sapiens)
• GeneID:4036
• Symbol:LRP2
• Description:LDL receptor related protein 2

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
4036	GO:0005509	IDA	enables	calcium ion binding	23275343	Function
4036	GO:0005515	IPI	enables	protein binding	9773776,23825075	Function
4036	GO:0038024	EXP	enables	cargo receptor activity	8710919,14528014	Function
4036	GO:0051087	IPI	enables	protein-folding chaperone binding	9228033	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
4036	GO:0005765	HDA	located_in	lysosomal membrane	17897319	Component
4036	GO:0016324	IDA	located_in	apical plasma membrane	23825075	Component
4036	GO:0043235	IDA	part_of	receptor complex	23382219	Component
4036	GO:0070062	HDA	located_in	extracellular exosome	19056867,23533145	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
4036	GO:0006898	IDA	involved_in	receptor-mediated endocytosis	23825075	Process
4036	GO:0015031	IDA	involved_in	protein transport	17324488	Process
4036	GO:0030001	IDA	involved_in	metal ion transport	15126248	Process
4036	GO:0043066	IGI	acts_upstream_of	negative regulation of apoptotic process	27241555	Process
4036	GO:0044321	IDA	involved_in	response to leptin	17324488	Process
4036	GO:0051897	IGI	involved_in	positive regulation of protein kinase B signaling	27241555	Process