Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:4041
  • Symbol:LRP5
  • Description:LDL receptor related protein 5

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
4041 GO:0002053 IMP involved_in positive regulation of mesenchymal cell proliferation 17680723 Process
4041 GO:0006007 IMP involved_in glucose catabolic process 19673927 Process
4041 GO:0008217 IMP involved_in regulation of blood pressure 18721193 Process
4041 GO:0008284 IDA involved_in positive regulation of cell population proliferation 9790987 Process
4041 GO:0042632 IMP involved_in cholesterol homeostasis 18721193,20146170 Process
4041 GO:0045600 IMP involved_in positive regulation of fat cell differentiation 17680723 Process
4041 GO:0045668 IMP involved_in negative regulation of osteoblast differentiation 17680723 Process
4041 GO:0045840 IDA involved_in positive regulation of mitotic nuclear division 9790987 Process
4041 GO:0045893 IDA involved_in positive regulation of DNA-templated transcription 15035989,17955262 Process
4041 GO:0045944 IDA involved_in positive regulation of transcription by RNA polymerase II 12857724 Process
4041 GO:0048539 IMP involved_in bone marrow development 17680723 Process
4041 GO:0060042 IMP involved_in retina morphogenesis in camera-type eye 15346351 Process
4041 GO:0060070 IDA involved_in canonical Wnt signaling pathway 11029007,12121999,12857724,15908424,24706814,25920554..... Process
4041 GO:0060070 IGI involved_in canonical Wnt signaling pathway 11336703,16805831 Process
4041 GO:0060070 IMP involved_in canonical Wnt signaling pathway 18044981,19673927 Process
4041 GO:0060349 IMP involved_in bone morphogenesis 19673927,20146170,20630166 Process
4041 GO:0060612 IMP involved_in adipose tissue development 17680723 Process
4041 GO:0061304 IMP involved_in retinal blood vessel morphogenesis 15024691,15346351 Process
4041 GO:0071901 IMP involved_in negative regulation of protein serine/threonine kinase activity 19107203 Process
4041 GO:0110135 IDA involved_in Norrin signaling pathway 15035989,17955262 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
4041 GO:0005515 IPI enables protein binding 11336703,11433302,15908424,18762581,20393562,21471202,28514442..... Function
4041 GO:0017147 IPI enables Wnt-protein binding 11336703 Function
4041 GO:0019534 IMP NOT enables toxin transmembrane transporter activity 18350154 Function
4041 GO:0042813 IDA enables Wnt receptor activity 24706814,25920554 Function
4041 GO:0071936 IPI enables coreceptor activity involved in Wnt signaling pathway 11336703 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
4041 GO:0005886 IDA located_in plasma membrane 17680723 Component
4041 GO:0043235 IDA part_of receptor complex 18762581 Component