Gene Ontology

Gene Info

• Species:Human (Homo sapiens)
• GeneID:4090
• Symbol:SMAD5
• Description:SMAD family member 5

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
4090	GO:0000978	IDA	enables	RNA polymerase II cis-regulatory region sequence-specific DNA binding	28369590	Function
4090	GO:0005515	IPI	enables	protein binding	15647271,18548003,25755279,32296183,32814053	Function
4090	GO:0017151	IPI	enables	DEAD/H-box RNA helicase binding	18548003	Function
4090	GO:0031625	IPI	enables	ubiquitin protein ligase binding	11278251	Function
4090	GO:1990837	IDA	enables	sequence-specific double-stranded DNA binding	28473536	Function

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
4090	GO:0001649	IDA	involved_in	osteoblast differentiation	30378100	Process
4090	GO:0010629	IMP	acts_upstream_of	negative regulation of gene expression	26400397	Process
4090	GO:0043066	IMP	involved_in	negative regulation of apoptotic process	26400397	Process
4090	GO:1902045	IMP	acts_upstream_of_or_within	negative regulation of Fas signaling pathway	26400397	Process

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
4090	GO:0005654	IDA	located_in	nucleoplasm		Component
4090	GO:0005829	IDA	located_in	cytosol		Component
4090	GO:0032991	IDA	part_of	protein-containing complex	23610558	Component