Gene Ontology

Gene Info

  • Species:Fly (Drosophila melanogaster)
  • GeneID:42737
  • Symbol:hh
  • Description:hedgehog

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
42737 GO:0001745 IMP involved_in compound eye morphogenesis 16651542 Process
42737 GO:0001746 IMP involved_in Bolwig's organ morphogenesis 10704398 Process
42737 GO:0002052 IMP involved_in positive regulation of neuroblast proliferation 12645928 Process
42737 GO:0002385 IMP involved_in mucosal immune response 25639794 Process
42737 GO:0007224 IDA involved_in smoothened signaling pathway 10409506,11486055,11495917,11934882,14523402,14636583,15598741..... Process
42737 GO:0007224 IGI involved_in smoothened signaling pathway 1653906,8700230,9874371,11090136,24931604 Process
42737 GO:0007224 IMP involved_in smoothened signaling pathway 7577671,8287482,15592457,17671093,19850026,20435030,29522397,3..... Process
42737 GO:0007280 IGI involved_in pole cell migration 16256738 Process
42737 GO:0007346 IMP involved_in regulation of mitotic cell cycle 11279500 Process
42737 GO:0007367 IEP involved_in segment polarity determination 1280560,8166882 Process
42737 GO:0007367 IMP involved_in segment polarity determination 7885476,8287482,8700230,15930099 Process
42737 GO:0007418 IMP involved_in ventral midline development 16467357 Process
42737 GO:0007427 IMP involved_in epithelial cell migration, open tracheal system 11290298 Process
42737 GO:0007442 IMP involved_in hindgut morphogenesis 11231061 Process
42737 GO:0007458 IEP involved_in progression of morphogenetic furrow involved in compound eye morphogenesis 8252628 Process
42737 GO:0007458 IGI involved_in progression of morphogenetic furrow involved in compound eye morphogenesis 8252628 Process
42737 GO:0007458 IMP involved_in progression of morphogenetic furrow involved in compound eye morphogenesis 8252628 Process
42737 GO:0007476 IMP involved_in imaginal disc-derived wing morphogenesis 8287482 Process
42737 GO:0007506 IMP involved_in gonadal mesoderm development 9435287 Process
42737 GO:0008347 IMP involved_in glial cell migration 11804568 Process
42737 GO:0008354 IDA NOT involved_in germ cell migration 19389345 Process
42737 GO:0008354 IMP involved_in germ cell migration 9435287 Process
42737 GO:0009880 IEP involved_in embryonic pattern specification 1394430 Process
42737 GO:0016335 IMP involved_in morphogenesis of larval imaginal disc epithelium 16236766 Process
42737 GO:0016540 IDA involved_in protein autoprocessing 7885476,9335337 Process
42737 GO:0016540 IMP involved_in protein autoprocessing 9335337 Process
42737 GO:0034111 IDA involved_in negative regulation of homotypic cell-cell adhesion 31209108 Process
42737 GO:0035154 IMP involved_in terminal cell fate specification, open tracheal system 24931604 Process
42737 GO:0035215 IMP involved_in genital disc development 15893978 Process
42737 GO:0035217 IMP involved_in labial disc development 15680366 Process
42737 GO:0035222 IDA involved_in wing disc pattern formation 20412775 Process
42737 GO:0035224 IEP involved_in genital disc anterior/posterior pattern formation 8798147 Process
42737 GO:0035231 IMP involved_in cytoneme assembly 10367889 Process
42737 GO:0035277 IMP involved_in spiracle morphogenesis, open tracheal system 15930099 Process
42737 GO:0045168 IMP involved_in cell-cell signaling involved in cell fate commitment 1280560 Process
42737 GO:0045861 IDA involved_in negative regulation of proteolysis 9215627 Process
42737 GO:0060914 IMP involved_in heart formation 8660881 Process
42737 GO:2000010 IDA involved_in positive regulation of protein localization to cell surface 19088085 Process
42737 GO:2000274 IMP involved_in regulation of epithelial cell migration, open tracheal system 24651658 Process
42737 GO:2000495 IMP involved_in regulation of cell proliferation involved in compound eye morphogenesis 17559828 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
42737 GO:0005113 IPI enables patched binding 20048000 Function
42737 GO:0005515 IPI enables protein binding 15691765,16630821,17077139,20048000,31209108 Function
42737 GO:0016015 IDA enables morphogen activity 20412775,21844892,22537496,28825565,36271509 Function
42737 GO:0016015 IMP enables morphogen activity 29522397 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
42737 GO:0005576 IDA located_in extracellular region 11486055 Component
42737 GO:0005615 IDA located_in extracellular space 8287482,12372301,17484784,18219274,22537496 Component
42737 GO:0005615 IMP located_in extracellular space 7552175 Component
42737 GO:0005634 IDA located_in nucleus 1280560 Component
42737 GO:0005737 IDA located_in cytoplasm 1280560 Component
42737 GO:0005768 IDA located_in endosome 17484784 Component
42737 GO:0005886 IDA located_in plasma membrane 17484784 Component
42737 GO:0030139 IDA located_in endocytic vesicle 18198278 Component
42737 GO:0031410 IDA located_in cytoplasmic vesicle 12586063 Component