Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:4297
  • Symbol:KMT2A
  • Description:lysine methyltransferase 2A

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
4297 GO:0005515 IPI enables protein binding 11313484,14992727,15199122,15960975,18840606,19187761,19556245..... Function
4297 GO:0008270 IDA enables zinc ion binding 16990798,19187761,29276034 Function
4297 GO:0042800 EXP enables histone H3K4 methyltransferase activity 22012064 Function
4297 GO:0042800 IDA enables histone H3K4 methyltransferase activity 19187761,19556245,24235145 Function
4297 GO:0042800 IMP enables histone H3K4 methyltransferase activity 15960975 Function
4297 GO:0042802 IPI enables identical protein binding 10656681,11313484 Function
4297 GO:0042803 IDA enables protein homodimerization activity 11313484 Function
4297 GO:0045322 IDA enables unmethylated CpG binding 16990798,20010842,29276034 Function
4297 GO:0070577 IDA enables lysine-acetylated histone binding 19187761 Function
4297 GO:0106363 IDA enables protein-cysteine methyltransferase activity 24235145 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
4297 GO:0005634 IDA located_in nucleus 11313484,15640349,22046413,25593309 Component
4297 GO:0005654 IDA located_in nucleoplasm Component
4297 GO:0005829 IDA located_in cytosol Component
4297 GO:0035097 IDA part_of histone methyltransferase complex 19556245 Component
4297 GO:0071339 IDA part_of MLL1 complex 15960975 Component
4297 GO:0071339 IPI part_of MLL1 complex 23508102 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
4297 GO:0032411 IMP involved_in positive regulation of transporter activity 20861184 Process
4297 GO:0040029 IMP involved_in epigenetic regulation of gene expression 20010842 Process
4297 GO:0045064 IDA involved_in T-helper 2 cell differentiation 20484083 Process
4297 GO:0045815 IDA involved_in transcription initiation-coupled chromatin remodeling 19556245 Process
4297 GO:0045815 IMP involved_in transcription initiation-coupled chromatin remodeling 15960975 Process
4297 GO:0045893 IMP involved_in positive regulation of DNA-templated transcription 15960975 Process
4297 GO:0045944 IDA involved_in positive regulation of transcription by RNA polymerase II 20861184 Process
4297 GO:0045944 IMP involved_in positive regulation of transcription by RNA polymerase II 20010842 Process
4297 GO:0065003 IDA involved_in protein-containing complex assembly 15199122 Process
4297 GO:0080182 IDA involved_in histone H3-K4 trimethylation 20861184 Process