Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:4301
  • Symbol:AFDN
  • Description:afadin, adherens junction formation factor

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
4301 GO:0005515 IPI enables protein binding 17491594,19461049,22891260,23750010,23885123,27815408,30463011..... Function
4301 GO:0031267 IPI enables small GTPase binding 23885123 Function
4301 GO:0045296 HDA enables cadherin binding 25468996 Function
4301 GO:0051015 IDA enables actin filament binding 16882694 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
4301 GO:0005654 IDA located_in nucleoplasm Component
4301 GO:0005829 IDA located_in cytosol Component
4301 GO:0005886 IDA located_in plasma membrane Component
4301 GO:0005911 IDA located_in cell-cell junction 19461049 Component
4301 GO:0016607 IDA located_in nuclear speck Component
4301 GO:0030054 IDA located_in cell junction Component
4301 GO:0044291 IDA located_in cell-cell contact zone 16882694 Component
4301 GO:0046930 IMP part_of pore complex 30463011 Component
4301 GO:0070160 IDA located_in tight junction 27815408 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
4301 GO:0010628 IMP involved_in positive regulation of gene expression 25893857 Process
4301 GO:0022409 IMP involved_in positive regulation of cell-cell adhesion 25893857 Process
4301 GO:0030336 IMP involved_in negative regulation of cell migration 21478912 Process
4301 GO:0046931 IMP involved_in pore complex assembly 30463011 Process
4301 GO:0070830 IMP involved_in bicellular tight junction assembly 27815408 Process
4301 GO:0090557 IMP involved_in establishment of endothelial intestinal barrier 23885123 Process
4301 GO:2000049 IMP involved_in positive regulation of cell-cell adhesion mediated by cadherin 16882694 Process