Gene Ontology

Gene Info

  • Species:Fly (Drosophila melanogaster)
  • GeneID:43222
  • Symbol:Tl
  • Description:Toll

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
43222 GO:0002225 IMP involved_in positive regulation of antimicrobial peptide production 8808632,9405661,10369678,31088910 Process
43222 GO:0002229 IMP involved_in defense response to oomycetes 23865688 Process
43222 GO:0002347 IMP involved_in response to tumor cell 24582964 Process
43222 GO:0002804 IDA involved_in positive regulation of antifungal peptide production 15197269 Process
43222 GO:0002804 IGI involved_in positive regulation of antifungal peptide production 8808632 Process
43222 GO:0007416 IMP involved_in synapse assembly 10699982 Process
43222 GO:0007507 IMP involved_in heart development 15870289 Process
43222 GO:0007526 IMP involved_in larval somatic muscle development 9676200 Process
43222 GO:0008063 IDA involved_in Toll signaling pathway 12872120,15197269,24282309 Process
43222 GO:0008063 IGI involved_in Toll signaling pathway 8846922 Process
43222 GO:0008063 IMP involved_in Toll signaling pathway 3931918,7705656,8808632,9025065,9736738,10369678,10973475,1243..... Process
43222 GO:0009597 IDA involved_in detection of virus 31088910 Process
43222 GO:0009611 IDA involved_in response to wounding 28289197 Process
43222 GO:0009950 IGI involved_in dorsal/ventral axis specification 3931918 Process
43222 GO:0009950 IMP involved_in dorsal/ventral axis specification 2449285,3931919,9025065,16782008 Process
43222 GO:0016201 IMP involved_in synaptic target inhibition 20504957 Process
43222 GO:0030308 IGI involved_in negative regulation of cell growth 29514084 Process
43222 GO:0030308 IMP involved_in negative regulation of cell growth 29514084 Process
43222 GO:0035208 IMP involved_in positive regulation of hemocyte proliferation 15882582 Process
43222 GO:0035212 IMP involved_in cell competition in a multicellular organism 30146479 Process
43222 GO:0040015 IMP involved_in negative regulation of multicellular organism growth 29514084 Process
43222 GO:0045087 IDA involved_in innate immune response 18583479 Process
43222 GO:0045087 IMP involved_in innate immune response 31088910 Process
43222 GO:0045944 IMP involved_in positive regulation of transcription by RNA polymerase II 25180232 Process
43222 GO:0046627 IGI acts_upstream_of negative regulation of insulin receptor signaling pathway 29514084 Process
43222 GO:0046627 IMP acts_upstream_of negative regulation of insulin receptor signaling pathway 29514084 Process
43222 GO:0050830 IDA involved_in defense response to Gram-positive bacterium 12872120 Process
43222 GO:0061760 IDA involved_in antifungal innate immune response 12872120 Process
43222 GO:0061760 IMP involved_in antifungal innate immune response 10973475 Process
43222 GO:1902875 IMP involved_in regulation of embryonic pattern specification 3931919 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
43222 GO:0004888 IDA enables transmembrane signaling receptor activity 15197269,24282309,31088910 Function
43222 GO:0004896 IMP enables cytokine receptor activity 12872120 Function
43222 GO:0005515 IPI enables protein binding 11881810,16782008,18347020 Function
43222 GO:0019955 IPI enables cytokine binding 12872120,17324925,24733933 Function
43222 GO:0046790 IDA enables virion binding 31088910 Function
43222 GO:0070976 IPI enables TIR domain binding 11743586 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
43222 GO:0005769 IDA located_in early endosome 20921412 Component
43222 GO:0005886 HDA located_in plasma membrane 19317464 Component
43222 GO:0005886 IDA located_in plasma membrane 1879347,7635064,19154721,20404143,31088910 Component
43222 GO:0009897 IDA located_in external side of plasma membrane 22464169 Component
43222 GO:0009986 IDA located_in cell surface 1879347 Component
43222 GO:0032154 IDA located_in cleavage furrow 1879347 Component