Gene Ontology

Gene Info

• Species:Mouse (Mus musculus)
• GeneID:433759
• Symbol:Hdac1
• Description:histone deacetylase 1

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
433759	GO:0000118	IPI	part_of	histone deacetylase complex	14645126	Component
433759	GO:0000785	IDA	part_of	chromatin	21093383	Component
433759	GO:0000792	IDA	part_of	heterochromatin	14519686,14643676	Component
433759	GO:0005634	IDA	located_in	nucleus	11115394,20720167,21874024,22770845	Component
433759	GO:0005667	IDA	part_of	transcription regulator complex	17707228	Component
433759	GO:0005667	IPI	part_of	transcription regulator complex	17182846	Component
433759	GO:0016581	IDA	part_of	NuRD complex	11836251,22075476	Component
433759	GO:0016581	IPI	part_of	NuRD complex	14645126,16462733	Component
433759	GO:0017053	IPI	part_of	transcription repressor complex	17182846	Component
433759	GO:0032991	IDA	part_of	protein-containing complex	19796622	Component
433759	GO:0043025	IDA	located_in	neuronal cell body	18651664	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
433759	GO:0000122	IDA	acts_upstream_of_or_within	negative regulation of transcription by RNA polymerase II	8917507,9271381	Process
433759	GO:0000122	IGI	involved_in	negative regulation of transcription by RNA polymerase II	21093383	Process
433759	GO:0007492	IDA	acts_upstream_of_or_within	endoderm development	15060137	Process
433759	GO:0007492	IMP	acts_upstream_of_or_within	endoderm development	15060137	Process
433759	GO:0007623	IDA	involved_in	circadian rhythm	24736997	Process
433759	GO:0008284	IGI	involved_in	positive regulation of cell population proliferation	21093383	Process
433759	GO:0009913	IGI	involved_in	epidermal cell differentiation	21093383	Process
433759	GO:0021766	IGI	acts_upstream_of_or_within	hippocampus development	19380719	Process
433759	GO:0030182	IGI	acts_upstream_of_or_within	neuron differentiation	19380719	Process
433759	GO:0032922	IDA	involved_in	circadian regulation of gene expression	15226430	Process
433759	GO:0042475	IGI	involved_in	odontogenesis of dentin-containing tooth	21093383	Process
433759	GO:0042733	IGI	involved_in	embryonic digit morphogenesis	21093383	Process
433759	GO:0043066	IGI	involved_in	negative regulation of apoptotic process	21093383	Process
433759	GO:0043124	IGI	acts_upstream_of_or_within	negative regulation of I-kappaB kinase/NF-kappaB signaling	19805123	Process
433759	GO:0045892	IDA	acts_upstream_of_or_within	negative regulation of DNA-templated transcription	9271381	Process
433759	GO:0045892	IDA	involved_in	negative regulation of DNA-templated transcription	21960634	Process
433759	GO:0048709	IGI	acts_upstream_of	oligodendrocyte differentiation	19503085	Process
433759	GO:0048714	IGI	acts_upstream_of_or_within	positive regulation of oligodendrocyte differentiation	19503085	Process
433759	GO:0060789	IGI	involved_in	hair follicle placode formation	21093383	Process
433759	GO:0061029	IGI	involved_in	eyelid development in camera-type eye	21093383	Process
433759	GO:0061198	IGI	involved_in	fungiform papilla formation	21093383	Process
433759	GO:0090090	IGI	acts_upstream_of_or_within	negative regulation of canonical Wnt signaling pathway	19503085	Process
433759	GO:2001243	IGI	acts_upstream_of_or_within	negative regulation of intrinsic apoptotic signaling pathway	21093383	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
433759	GO:0000976	IDA	enables	transcription cis-regulatory region binding	24413057	Function
433759	GO:0003677	IDA	enables	DNA binding	14593184	Function
433759	GO:0003682	IDA	enables	chromatin binding	15608638,16109736,16678101,17392792,17905753	Function
433759	GO:0003714	IDA	enables	transcription corepressor activity	8917507,15509593	Function
433759	GO:0004407	IDA	enables	histone deacetylase activity	10615135,21960634,30279482	Function
433759	GO:0005515	IPI	enables	protein binding	8917507,9139821,10615135,11115394,11641275,11836251,11923873,1.....	Function
433759	GO:0035851	IPI	enables	Krueppel-associated box domain binding	21177534	Function
433759	GO:0061629	IPI	enables	RNA polymerase II-specific DNA-binding transcription factor binding	19235719	Function
433759	GO:0070888	IDA	enables	E-box binding	24736997	Function
433759	GO:0140297	IPI	enables	DNA-binding transcription factor binding	18486321,33795231	Function
433759	GO:0160009	IDA	enables	histone decrotonylase activity	30279482	Function
433759	GO:1990841	IDA	enables	promoter-specific chromatin binding	22770845	Function