Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:4627
  • Symbol:MYH9
  • Description:myosin heavy chain 9

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
4627 GO:0000146 IDA contributes_to microfilament motor activity 24072716 Function
4627 GO:0000146 IDA enables microfilament motor activity 12237319,15845534 Function
4627 GO:0003723 HDA enables RNA binding 22681889 Function
4627 GO:0003779 IDA enables actin binding 15065866 Function
4627 GO:0005178 IDA enables integrin binding 10822899 Function
4627 GO:0005515 IPI enables protein binding 2732579,10822899,12202484,12421915,12577067,14508515,14640694,..... Function
4627 GO:0005524 IDA enables ATP binding 15065866,15845534 Function
4627 GO:0019904 IPI enables protein domain specific binding 23325791 Function
4627 GO:0042802 IPI enables identical protein binding 22483112,31837246 Function
4627 GO:0042803 IDA enables protein homodimerization activity 12237319 Function
4627 GO:0043495 IMP enables protein-membrane adaptor activity 16403913 Function
4627 GO:0043531 IDA enables ADP binding 15065866 Function
4627 GO:0045296 HDA enables cadherin binding 25468996 Function
4627 GO:0051015 IDA contributes_to actin filament binding 24072716 Function
4627 GO:0051015 IDA enables actin filament binding 12237319,14508515,15845534 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
4627 GO:0001525 IDA involved_in angiogenesis 16403913 Process
4627 GO:0001778 IDA involved_in plasma membrane repair 27325790 Process
4627 GO:0006509 IDA involved_in membrane protein ectodomain proteolysis 16186248 Process
4627 GO:0008360 IMP involved_in regulation of cell shape 11029059 Process
4627 GO:0015031 IMP involved_in protein transport 16403913 Process
4627 GO:0030036 IMP involved_in actin cytoskeleton organization 15869600 Process
4627 GO:0030048 IDA acts_upstream_of_or_within actin filament-based movement 15845534 Process
4627 GO:0030048 IDA involved_in actin filament-based movement 12237319 Process
4627 GO:0030220 IMP involved_in platelet formation 12237319 Process
4627 GO:0030224 IEP involved_in monocyte differentiation 1912569 Process
4627 GO:0031032 IDA involved_in actomyosin structure organization 24072716 Process
4627 GO:0032418 IMP involved_in lysosome localization 2732579 Process
4627 GO:0032506 IMP involved_in cytokinetic process 15774463 Process
4627 GO:0043534 IMP involved_in blood vessel endothelial cell migration 16403913 Process
4627 GO:0045055 IMP involved_in regulated exocytosis 2732579 Process
4627 GO:0070527 HMP involved_in platelet aggregation 23382103 Process
4627 GO:1903919 IMP involved_in negative regulation of actin filament severing 23325791 Process
4627 GO:1905684 IMP involved_in regulation of plasma membrane repair 2732579 Process

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
4627 GO:0001725 IDA located_in stress fiber 7699007,14508515,14706930,15774463,16403913 Component
4627 GO:0001726 IDA located_in ruffle 16403913 Component
4627 GO:0001772 IDA located_in immunological synapse 15064761 Component
4627 GO:0001931 IDA located_in uropod 15064761 Component
4627 GO:0005634 IDA located_in nucleus 14508515 Component
4627 GO:0005737 IDA located_in cytoplasm 7699007,22693546 Component
4627 GO:0005826 IDA located_in actomyosin contractile ring 11029059 Component
4627 GO:0005829 IDA located_in cytosol 14508515 Component
4627 GO:0005886 IDA located_in plasma membrane 16186248,16403913 Component
4627 GO:0009898 IDA located_in cytoplasmic side of plasma membrane 15064761 Component
4627 GO:0015629 IDA located_in actin cytoskeleton 15869600 Component
4627 GO:0016020 HDA located_in membrane 19946888 Component
4627 GO:0016460 IDA part_of myosin II complex 24072716 Component
4627 GO:0016604 IDA located_in nuclear body Component
4627 GO:0031252 IDA located_in cell leading edge 12421915 Component
4627 GO:0032154 IDA located_in cleavage furrow 7699007,14508515 Component
4627 GO:0032991 IDA part_of protein-containing complex 12421915 Component
4627 GO:0042641 IDA located_in actomyosin 24072716 Component
4627 GO:0070062 HDA located_in extracellular exosome 19056867,19199708,20458337,21362503,23533145 Component
4627 GO:0097513 IDA located_in myosin II filament 24072716 Component