Gene Ontology

Gene Info

• Species:Human (Homo sapiens)
• GeneID:476
• Symbol:ATP1A1
• Description:ATPase Na+/K+ transporting subunit alpha 1

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
476	GO:0005391	IDA	enables	P-type sodium:potassium-exchanging transporter activity	10636900,19542013	Function
476	GO:0005391	IGI	enables	P-type sodium:potassium-exchanging transporter activity	18052210	Function
476	GO:0005515	IPI	enables	protein binding	11027149,15671290,16730713,18504258,21278788,22084111,25012180.....	Function
476	GO:0051087	IPI	enables	protein-folding chaperone binding	10636900	Function
476	GO:1990239	IDA	enables	steroid hormone binding	14742675	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
476	GO:0005886	HDA	located_in	plasma membrane	16791210	Component
476	GO:0005886	IDA	located_in	plasma membrane	7711835,18522992	Component
476	GO:0005886	IGI	located_in	plasma membrane	19751721	Component
476	GO:0005890	IDA	part_of	sodium:potassium-exchanging ATPase complex	10636900,19542013	Component
476	GO:0005890	IGI	part_of	sodium:potassium-exchanging ATPase complex	18052210	Component
476	GO:0016324	IDA	located_in	apical plasma membrane	11193188	Component
476	GO:0016328	IDA	located_in	lateral plasma membrane	11193188	Component
476	GO:0030315	IGI	located_in	T-tubule	19751721	Component
476	GO:0031090	IGI	located_in	organelle membrane	19751721	Component
476	GO:0032991	IDA	part_of	protein-containing complex	22797923	Component
476	GO:0036126	IDA	located_in	sperm flagellum	16861705	Component
476	GO:0070062	HDA	located_in	extracellular exosome	12519789,19199708,20458337	Component
476	GO:1903561	HDA	located_in	extracellular vesicle	24769233	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
476	GO:0006883	IDA	involved_in	intracellular sodium ion homeostasis	10636900,19542013	Process
476	GO:0030007	IDA	involved_in	intracellular potassium ion homeostasis	10636900,19542013	Process
476	GO:0036376	IDA	involved_in	sodium ion export across plasma membrane	10636900,19542013	Process
476	GO:0071383	IDA	involved_in	cellular response to steroid hormone stimulus	11546672	Process
476	GO:0086009	IDA	involved_in	membrane repolarization	19542013	Process
476	GO:1903416	IDA	involved_in	response to glycoside	11546672	Process
476	GO:1990573	IDA	involved_in	potassium ion import across plasma membrane	10636900,19542013	Process