Gene Ontology

Gene Info

• Species:Human (Homo sapiens)
• GeneID:477
• Symbol:ATP1A2
• Description:ATPase Na+/K+ transporting subunit alpha 2

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
477	GO:0005391	IDA	enables	P-type sodium:potassium-exchanging transporter activity	10636900	Function
477	GO:0005391	IGI	enables	P-type sodium:potassium-exchanging transporter activity	18052210,18728015,20100892	Function
477	GO:0005391	IMP	enables	P-type sodium:potassium-exchanging transporter activity	12539047,23954377	Function
477	GO:0005496	IPI	enables	steroid binding	23954377	Function
477	GO:0005515	IPI	enables	protein binding	23954377	Function
477	GO:0005524	IMP	enables	ATP binding	23954377	Function
477	GO:0016887	IMP	enables	ATP hydrolysis activity	23954377	Function
477	GO:0019829	IDA	enables	ATPase-coupled monoatomic cation transmembrane transporter activity	19372756	Function
477	GO:0019829	IGI	enables	ATPase-coupled monoatomic cation transmembrane transporter activity	20100892	Function
477	GO:0030955	IMP	enables	potassium ion binding	23954377	Function
477	GO:0031402	IMP	enables	sodium ion binding	23954377	Function
477	GO:0051087	IPI	enables	protein-folding chaperone binding	10636900	Function
477	GO:1990239	IDA	enables	steroid hormone binding	14742675	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
477	GO:0005737	IDA	located_in	cytoplasm	12539047	Component
477	GO:0005886	IDA	located_in	plasma membrane	12539047	Component
477	GO:0005886	IGI	located_in	plasma membrane	19372756,19751721	Component
477	GO:0005890	IDA	part_of	sodium:potassium-exchanging ATPase complex	10636900,23954377	Component
477	GO:0005890	IGI	part_of	sodium:potassium-exchanging ATPase complex	18052210,18728015	Component
477	GO:0016020	IDA	located_in	membrane	23954377	Component
477	GO:0030315	IGI	located_in	T-tubule	19751721	Component
477	GO:0031090	IGI	located_in	organelle membrane	19751721	Component
477	GO:1903561	HDA	located_in	extracellular vesicle	24769233	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
477	GO:0006883	IDA	involved_in	intracellular sodium ion homeostasis	10636900	Process
477	GO:0030007	IDA	involved_in	intracellular potassium ion homeostasis	10636900	Process
477	GO:0035725	IGI	involved_in	sodium ion transmembrane transport	18728015	Process
477	GO:0036376	IDA	involved_in	sodium ion export across plasma membrane	10636900	Process
477	GO:0046034	IMP	involved_in	ATP metabolic process	23954377	Process
477	GO:0071383	IDA	involved_in	cellular response to steroid hormone stimulus	14742675	Process
477	GO:0071805	IGI	involved_in	potassium ion transmembrane transport	18728015	Process
477	GO:0098655	IDA	involved_in	monoatomic cation transmembrane transport	19372756	Process
477	GO:0098655	IGI	involved_in	monoatomic cation transmembrane transport	20100892	Process
477	GO:1990573	IDA	involved_in	potassium ion import across plasma membrane	10636900	Process