Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:4853
  • Symbol:NOTCH2
  • Description:notch receptor 2

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
4853 GO:0003184 IMP involved_in pulmonary valve morphogenesis 16773578 Process
4853 GO:0007219 IDA involved_in Notch signaling pathway 11306509,25985737 Process
4853 GO:0009887 IEP involved_in animal organ morphogenesis 12531696 Process
4853 GO:0010629 IDA involved_in negative regulation of gene expression 11306509 Process
4853 GO:0010838 IDA involved_in positive regulation of keratinocyte proliferation 18469519 Process
4853 GO:0035556 IDA involved_in intracellular signal transduction 18469519 Process
4853 GO:0046579 IDA involved_in positive regulation of Ras protein signal transduction 11306509 Process
4853 GO:0046849 IMP involved_in bone remodeling 21378985,21378989 Process
4853 GO:0060413 IMP involved_in atrial septum morphogenesis 16773578 Process
4853 GO:0070374 IDA involved_in positive regulation of ERK1 and ERK2 cascade 11306509 Process
4853 GO:0071228 IDA involved_in cellular response to tumor cell 11306509 Process
4853 GO:2001204 IMP involved_in regulation of osteoclast development 29149593 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
4853 GO:0005515 IPI enables protein binding 10079256,11101851,11823422,18469519,25985737,29149593,29329397..... Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
4853 GO:0005634 IDA located_in nucleus 1303260 Component
4853 GO:0005654 IDA located_in nucleoplasm Component
4853 GO:0005886 IDA located_in plasma membrane 9244302,29329397 Component
4853 GO:0009986 IDA located_in cell surface 9244302 Component
4853 GO:0016020 HDA located_in membrane 19946888 Component
4853 GO:0043235 IDA part_of receptor complex 23382219 Component