Gene Ontology

Gene Info

• Species:Human (Homo sapiens)
• GeneID:4921
• Symbol:DDR2
• Description:discoidin domain receptor tyrosine kinase 2

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
4921	GO:0004714	IDA	enables	transmembrane receptor protein tyrosine kinase activity	20004161	Function
4921	GO:0005515	IPI	enables	protein binding	17703188,22939624,25036637,35384245	Function
4921	GO:0005518	IDA	enables	collagen binding	20004161	Function
4921	GO:0038062	IDA	enables	protein tyrosine kinase collagen receptor activity	9659899	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
4921	GO:0005886	IDA	located_in	plasma membrane		Component
4921	GO:0005925	HDA	located_in	focal adhesion	21423176	Component
4921	GO:0015629	IDA	located_in	actin cytoskeleton		Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
4921	GO:0018108	IDA	involved_in	peptidyl-tyrosine phosphorylation	20004161	Process
4921	GO:0030500	IMP	involved_in	regulation of bone mineralization	20564243	Process
4921	GO:0034103	IMP	involved_in	regulation of tissue remodeling	30449416	Process
4921	GO:0038063	IDA	involved_in	collagen-activated tyrosine kinase receptor signaling pathway	16186108	Process
4921	GO:0045669	IMP	involved_in	positive regulation of osteoblast differentiation	20564243	Process
4921	GO:0045860	IMP	involved_in	positive regulation of protein kinase activity	20564243	Process
4921	GO:0046777	IDA	involved_in	protein autophosphorylation	16186108	Process
4921	GO:0051091	IMP	involved_in	positive regulation of DNA-binding transcription factor activity	20564243	Process