Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:5062
  • Symbol:PAK2
  • Description:p21 (RAC1) activated kinase 2

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5062 GO:0004674 EXP enables protein serine/threonine kinase activity 11278486,17060906 Function
5062 GO:0004674 IDA enables protein serine/threonine kinase activity 11121037,11805089,21555521,27889207 Function
5062 GO:0004674 IMP enables protein serine/threonine kinase activity 33693784 Function
5062 GO:0005515 IPI enables protein binding 10607567,16374509,16527308,16787945,16837009,18716323,19240112..... Function
5062 GO:0019901 IPI enables protein kinase binding 11121037 Function
5062 GO:0030296 IDA enables protein tyrosine kinase activator activity 11121037 Function
5062 GO:0031267 IPI enables small GTPase binding 8625410 Function
5062 GO:0042802 IPI enables identical protein binding 16837009 Function
5062 GO:0045296 HDA enables cadherin binding 25468996 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5062 GO:0005634 IDA is_active_in nucleus 21555521 Component
5062 GO:0005737 IDA is_active_in cytoplasm 21555521 Component
5062 GO:0005737 IDA located_in cytoplasm 25468996 Component
5062 GO:0005829 IDA located_in cytosol 8625410 Component
5062 GO:0005911 IMP located_in cell-cell junction 25753039 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5062 GO:0006468 IDA acts_upstream_of_or_within protein phosphorylation 11805089 Process
5062 GO:0016310 IDA involved_in phosphorylation 21555521 Process
5062 GO:0018105 IDA involved_in peptidyl-serine phosphorylation 11121037 Process
5062 GO:0034333 IMP involved_in adherens junction assembly 25753039 Process
5062 GO:0043066 IDA involved_in negative regulation of apoptotic process 21555521,27889207 Process
5062 GO:0043066 IMP involved_in negative regulation of apoptotic process 21555521 Process
5062 GO:0046777 IDA acts_upstream_of_or_within protein autophosphorylation 11805089 Process
5062 GO:0050731 IDA involved_in positive regulation of peptidyl-tyrosine phosphorylation 11121037 Process
5062 GO:0051179 IMP involved_in localization 31391252 Process
5062 GO:0051493 IMP involved_in regulation of cytoskeleton organization 25753039 Process
5062 GO:0051497 IMP involved_in negative regulation of stress fiber assembly 25753039 Process
5062 GO:0070830 IMP involved_in bicellular tight junction assembly 25753039 Process
5062 GO:0150105 IMP involved_in protein localization to cell-cell junction 25753039 Process
5062 GO:2001238 IMP involved_in positive regulation of extrinsic apoptotic signaling pathway 19240112 Process
5062 GO:2001271 IDA involved_in negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis 21555521 Process