Gene Ontology

Gene Info

• Species:Human (Homo sapiens)
• GeneID:51567
• Symbol:TDP2
• Description:tyrosyl-DNA phosphodiesterase 2

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
51567	GO:0000287	IDA	enables	magnesium ion binding	22405347,22822062	Function
51567	GO:0003697	IDA	enables	single-stranded DNA binding	22822062	Function
51567	GO:0005515	IPI	enables	protein binding	18039968,32296183,32814053	Function
51567	GO:0030145	IDA	enables	manganese ion binding	22822062	Function
51567	GO:0036317	IDA	enables	tyrosyl-RNA phosphodiesterase activity	22908287	Function
51567	GO:0070260	IDA	enables	5'-tyrosyl-DNA phosphodiesterase activity	19794497,22405347,22822062	Function
51567	GO:0070260	IMP	enables	5'-tyrosyl-DNA phosphodiesterase activity	21030584	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
51567	GO:0005634	IDA	located_in	nucleus	22908287	Component
51567	GO:0005654	IDA	located_in	nucleoplasm		Component
51567	GO:0005737	IDA	located_in	cytoplasm	22908287	Component
51567	GO:0016235	IDA	located_in	aggresome		Component
51567	GO:0016604	IDA	located_in	nuclear body		Component
51567	GO:0016605	IDA	located_in	PML body	19794497	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
51567	GO:0006302	IDA	involved_in	double-strand break repair	19794497	Process
51567	GO:0006302	IMP	involved_in	double-strand break repair	21030584	Process
51567	GO:0048666	IMP	involved_in	neuron development	24658003	Process