Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:5159
  • Symbol:PDGFRB
  • Description:platelet derived growth factor receptor beta

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5159 GO:0004713 IDA enables protein tyrosine kinase activity 1653029 Function
5159 GO:0005019 IDA enables platelet-derived growth factor beta-receptor activity 1314164,2536956,2850496 Function
5159 GO:0005019 IMP enables platelet-derived growth factor beta-receptor activity 2554309,26599395 Function
5159 GO:0005102 IPI enables signaling receptor binding 10821867 Function
5159 GO:0005161 IPI enables platelet-derived growth factor receptor binding 2542288 Function
5159 GO:0005515 IPI enables protein binding 1314164,1330535,1334459,1375321,1396585,1661130,2157284,753004..... Function
5159 GO:0019899 IPI enables enzyme binding 26315405 Function
5159 GO:0019901 IPI enables protein kinase binding 16479011 Function
5159 GO:0038085 IPI enables vascular endothelial growth factor binding 17470632 Function
5159 GO:0048407 IDA enables platelet-derived growth factor binding 2554309,2850496 Function
5159 GO:0048407 IPI enables platelet-derived growth factor binding 2536956 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5159 GO:0005794 IDA located_in Golgi apparatus Component
5159 GO:0005886 IDA located_in plasma membrane 2554309 Component
5159 GO:0005925 HDA located_in focal adhesion 21423176 Component
5159 GO:0016020 HDA located_in membrane 19946888 Component
5159 GO:0016020 IDA located_in membrane 16477012 Component
5159 GO:0043231 IDA located_in intracellular membrane-bounded organelle Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5159 GO:0007165 IDA involved_in signal transduction 10821867 Process
5159 GO:0008284 IMP involved_in positive regulation of cell population proliferation 2554309 Process
5159 GO:0010863 IDA involved_in positive regulation of phospholipase C activity 1653029 Process
5159 GO:0014911 IMP involved_in positive regulation of smooth muscle cell migration 21679854 Process
5159 GO:0016477 IMP involved_in cell migration 2554309 Process
5159 GO:0018108 IDA involved_in peptidyl-tyrosine phosphorylation 1653029,2536956,2850496 Process
5159 GO:0030335 IDA involved_in positive regulation of cell migration 17470632 Process
5159 GO:0032516 IDA involved_in positive regulation of phosphoprotein phosphatase activity 7691811 Process
5159 GO:0035791 IMP involved_in platelet-derived growth factor receptor-beta signaling pathway 2554309,26599395 Process
5159 GO:0038091 IDA involved_in positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway 17470632 Process
5159 GO:0043552 IDA involved_in positive regulation of phosphatidylinositol 3-kinase activity 1314164 Process
5159 GO:0046488 IMP involved_in phosphatidylinositol metabolic process 1653029 Process
5159 GO:0046777 IDA involved_in protein autophosphorylation 1314164,2536956,2850496 Process
5159 GO:0048008 IDA involved_in platelet-derived growth factor receptor signaling pathway 1314164,2536956 Process
5159 GO:0048015 IMP involved_in phosphatidylinositol-mediated signaling 2554309 Process
5159 GO:0048661 IMP involved_in positive regulation of smooth muscle cell proliferation 21679854 Process
5159 GO:0060326 IDA involved_in cell chemotaxis 2554309,17991872 Process
5159 GO:0070374 IMP involved_in positive regulation of ERK1 and ERK2 cascade 21679854 Process