Gene Ontology

Gene Info

• Species:Human (Homo sapiens)
• GeneID:51776
• Symbol:MAP3K20
• Description:mitogen-activated protein kinase kinase kinase 20

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
51776	GO:0000077	IMP	involved_in	DNA damage checkpoint signaling	11836244	Process
51776	GO:0006468	IDA	involved_in	protein phosphorylation	11836244	Process
51776	GO:0007254	IDA	involved_in	JNK cascade	11836244,12220515,14521931,15737997,32610081	Process
51776	GO:0031098	IDA	involved_in	stress-activated protein kinase signaling cascade	15737997,18331592,20559024,32610081,35857590	Process
51776	GO:0038066	IDA	involved_in	p38MAPK cascade	11836244,15737997,32610081,35857590	Process
51776	GO:0042733	IMP	involved_in	embryonic digit morphogenesis	26755636	Process
51776	GO:0043065	IDA	involved_in	positive regulation of apoptotic process	10924358	Process
51776	GO:0043068	IDA	acts_upstream_of	positive regulation of programmed cell death	32289254,32610081	Process
51776	GO:0046777	IDA	involved_in	protein autophosphorylation	12220515,32289254,32610081	Process
51776	GO:0051403	IDA	involved_in	stress-activated MAPK cascade	11836244,32289254,32610081	Process
51776	GO:0060173	IMP	involved_in	limb development	26755636	Process
51776	GO:0070269	IDA	acts_upstream_of_positive_effect	pyroptosis	35857590	Process
51776	GO:0071480	IDA	involved_in	cellular response to gamma radiation	11836244	Process
51776	GO:0071493	IDA	involved_in	cellular response to UV-B	35857590	Process
51776	GO:0140469	IDA	acts_upstream_of	GCN2-mediated signaling	32610081	Process
51776	GO:1904291	IDA	involved_in	positive regulation of mitotic DNA damage checkpoint	15342622	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
51776	GO:0000287	IDA	enables	magnesium ion binding	11836244	Function
51776	GO:0003723	HDA	enables	RNA binding	22681889	Function
51776	GO:0004674	IDA	enables	protein serine/threonine kinase activity	35857590	Function
51776	GO:0004706	IDA	enables	JUN kinase kinase kinase activity	11836244,12220515,14521931,32610081	Function
51776	GO:0004709	IDA	enables	MAP kinase kinase kinase activity	11836244,15737997,32289254,32610081,35857590	Function
51776	GO:0005515	IPI	enables	protein binding	16189514,21516116,21988832,28514442,31515488	Function
51776	GO:0005524	IDA	enables	ATP binding	11836244	Function
51776	GO:0030295	IDA	enables	protein kinase activator activity	32610081	Function
51776	GO:0043022	IDA	enables	ribosome binding	32289254,32610081	Function
51776	GO:0070181	IDA	enables	small ribosomal subunit rRNA binding	32289254	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
51776	GO:0005829	IDA	located_in	cytosol		Component