Gene Ontology

Gene Info

• Species:Human (Homo sapiens)
• GeneID:5290
• Symbol:PIK3CA
• Description:phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
5290	GO:0005515	IPI	enables	protein binding	10490823,16043515,17475214,18079394,19380743,19411071,19574958.....	Function
5290	GO:0016301	IDA	enables	kinase activity	25327288	Function
5290	GO:0016303	IDA	enables	1-phosphatidylinositol-3-kinase activity	2174051	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
5290	GO:0005943	IDA	part_of	phosphatidylinositol 3-kinase complex, class IA	22402981	Component
5290	GO:0005943	IPI	part_of	phosphatidylinositol 3-kinase complex, class IA	19805105	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
5290	GO:0014065	IGI	involved_in	phosphatidylinositol 3-kinase signaling	30496354	Process
5290	GO:0016310	IDA	acts_upstream_of_or_within	phosphorylation	25327288	Process
5290	GO:0038084	IGI	involved_in	vascular endothelial growth factor signaling pathway	30496354	Process
5290	GO:0051897	IGI	involved_in	positive regulation of protein kinase B signaling	30496354	Process
5290	GO:2000811	IMP	involved_in	negative regulation of anoikis	22402981	Process